ID R7VWY4_COLLI Unreviewed; 858 AA.
AC R7VWY4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Scm-like with four MBT domains protein 1 {ECO:0000313|EMBL:EMC85227.1};
DE Flags: Fragment;
GN ORFNames=A306_06385 {ECO:0000313|EMBL:EMC85227.1};
OS Columba livia (Rock dove).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Columbiformes; Columbidae; Columba.
OX NCBI_TaxID=8932 {ECO:0000313|EMBL:EMC85227.1};
RN [1] {ECO:0000313|EMBL:EMC85227.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Blood {ECO:0000313|EMBL:EMC85227.1};
RX PubMed=23371554; DOI=10.1126/science.1230422;
RA Shapiro M.D., Kronenberg Z., Li C., Domyan E.T., Pan H., Campbell M.,
RA Tan H., Huff C.D., Hu H., Vickrey A.I., Nielsen S.C., Stringham S.A.,
RA Hu H., Willerslev E., Gilbert M.T., Yandell M., Zhang G., Wang J.;
RT "Genomic diversity and evolution of the head crest in the rock pigeon.";
RL Science 339:1063-1067(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KB375538; EMC85227.1; -; Genomic_DNA.
DR AlphaFoldDB; R7VWY4; -.
DR eggNOG; KOG3766; Eukaryota.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd20111; MBT_SFMBT1_rpt1; 1.
DR CDD; cd20113; MBT_SFMBT1_rpt2; 1.
DR CDD; cd20115; MBT_SFMBT1_rpt3; 1.
DR CDD; cd20117; MBT_SFMBT1_rpt4; 1.
DR CDD; cd09581; SAM_Scm-like-4MBT1_2; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR047352; MBT_SFMBT1_rpt2.
DR InterPro; IPR047351; MBT_SFMBT1_rpt3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037604; Scm-like-4MBT1/2_SAM.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF77; SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1; 1.
DR Pfam; PF02820; MBT; 4.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 4.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS51079; MBT; 4.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 11..111
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 119..223
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 233..340
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 348..445
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 785..851
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
FT REGION 633..769
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..671
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..709
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..726
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 741..769
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EMC85227.1"
SQ SEQUENCE 858 AA; 96575 MW; 343BC91C642C39F8 CRC64;
DAGSSVEEME FNWDEYLEDT GATAAPHGSF KHVDTSLQNG FAPGMKLEVA VKSDQNTYWV
ATIITTCGQL LLLRYDGYGE DRKADFWCDI MTADLHPIGW CEQNKKILKV PEGIKDKIPD
QEEFLQRVLK GACSAPANLL EGLHRGKNPL DLIAPGSRLE LQNTRDSLAA WIVNVVENVG
GRLKLRYEGL EDSDKFDQWI FYLDPFLHQV GWAAQHGYSL QPPLAIRSLK SEADWQVILK
KVKEEEEESS VPTDLFKDKP VIGVHAFSEG MKLEAVDPMA PFIISPATVV KVFNEKYFMI
EIDDLRAERT TSRSYICHVN SAGIFPVQWS LKNGLHLSPP PGYPGQDFDW ADYLKQCGAE
AAPQSCFPSL TSDHGFKENM KLEAVNPVDP EEVCIATVTK LRDSYLWLQL EGSKKPIPDC
IVSVESMNIF PVGWCETNGY QLRPPRKAIV NKQKKIAVVQ PEKQILSSRT VHDGLKNQEL
NSSDSVVING KYCCPKIYFN HRCFSGPYLN KGRIAELPQS VGPGNCVLVL KEVLTLLINA
AYKPSRVLRE LQLDEEAAWH GHGETLKAKY KGKSYRATVE VVRTADRVAD FCRKTCIKLE
CCPNLFGPQM VLDKCSENCS VLTKTKYTHY YGKRKNKRIG RPPGGHSNLE VAMKKPNKRR
KRRKHFFVHK KKRSSASVDN TPAGSPQGSG GEEDDDQDEV DEESLTEDST SEHQDELLEE
SEVSEKKSLS SSPTQSELSH SLAQDRDKRK RKLRTFSFSD DENKPPSPKD IKMEVAEKLQ
LDSNPLEWSV ADVVRFLKST DCAPLARIFL DQEIDGQALL LLTLPTVQEC MDLKLGPAIK
LCHHIERVKL AFYQQFAN
//
