ID   R7W4I5_AEGTA            Unreviewed;       548 AA.
AC   R7W4I5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 54.
DE   SubName: Full=Aspartic proteinase oryzasin-1 {ECO:0000313|EnsemblPlants:EMT14628};
OS   Aegilops tauschii (Tausch's goatgrass) (Aegilops squarrosa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Triticinae; Aegilops.
OX   NCBI_TaxID=37682 {ECO:0000313|EnsemblPlants:EMT14628};
RN   [1] {ECO:0000313|EnsemblPlants:EMT14628}
RP   IDENTIFICATION.
RG   EnsemblPlants;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase A1 family.
CC       {ECO:0000256|ARBA:ARBA00007447, ECO:0000256|RuleBase:RU000454}.
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DR   AlphaFoldDB; R7W4I5; -.
DR   EnsemblPlants; EMT14628; EMT14628; F775_06381.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.70.10; Acid Proteases; 2.
DR   Gene3D; 1.10.225.10; Saposin-like; 1.
DR   InterPro; IPR001461; Aspartic_peptidase_A1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR033121; PEPTIDASE_A1.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR007856; SapB_1.
DR   InterPro; IPR008138; SapB_2.
DR   InterPro; IPR011001; Saposin-like.
DR   InterPro; IPR008139; SaposinB_dom.
DR   PANTHER; PTHR47966; BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED; 1.
DR   PANTHER; PTHR47966:SF50; OS01G0631900 PROTEIN; 1.
DR   Pfam; PF00026; Asp; 1.
DR   Pfam; PF05184; SapB_1; 1.
DR   Pfam; PF03489; SapB_2; 1.
DR   PRINTS; PR00792; PEPSIN.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF47862; Saposin; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 2.
DR   PROSITE; PS51767; PEPTIDASE_A1; 1.
DR   PROSITE; PS50015; SAP_B; 2.
PE   3: Inferred from homology;
KW   Aspartyl protease {ECO:0000256|ARBA:ARBA00022750,
KW   ECO:0000256|RuleBase:RU000454};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW   ECO:0000256|PIRSR:PIRSR601461-2};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000454};
KW   Protease {ECO:0000256|RuleBase:RU000454}.
FT   ACT_SITE        142
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT   ACT_SITE        329
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-1"
FT   DISULFID        155..161
FT                   /evidence="ECO:0000256|PIRSR:PIRSR601461-2"
SQ   SEQUENCE   548 AA;  59728 MW;  96270C749B8216C3 CRC64;
     MGQHGIRGIC TILSVILASS TLVSAGDDGL VRIALKKRPV MQDIYNKPVP KSTTENSGAG
     REVDPVREAV NQVRAQAQRI FTEAAAMERR LKRRWSHRGI GGNRRVREGY QAVVPLKNYV
     NAQYFGQIGV GSPPQNFTVV FDTGSANLWV PSAECFFSLA CYFHPKYVSR RSSTYKENGT
     PASIHYGKGA IFGFYSQDQV TIGDLVVNNQ EFIEATYEPG FTFLAAKFDG ILGLGFKEIS
     VEGSVPVWYN MIAQGLVNQH VFSFWLNRNA NNGDGGEIVF GGSDPKHYKG SHTYTRVTRK
     AYWQFEMGDF LIGGKSTGIC VDGCAAIADS GTSLIAGPIG VIAQINERIG ATGVANKECK
     QVVSGYGQEM IELLKSETPP AQVCSKIGLC AFDGTSGVSA GIKRVTGEGR TTSVHNMFDA
     TCNACEMVVT WMQSEFVQNH TKEGMLEYVD RLCHNMPSPM GSYVDCRHID SLQSVSFSIG
     GRIFELQPEQ QYILKVGDGF VAHCISGFTS LDIPPPVGPL WILGDVFMGA YHTVFDYDKM
     SVGFAASA
//