ID R7XTZ5_9ACTN Unreviewed; 331 AA.
AC R7XTZ5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=UDP-glucose 4-epimerase {ECO:0000256|ARBA:ARBA00018569};
DE EC=5.1.3.2 {ECO:0000256|ARBA:ARBA00013189};
DE AltName: Full=UDP-galactose 4-epimerase {ECO:0000256|ARBA:ARBA00031367};
GN ORFNames=CF8_3352 {ECO:0000313|EMBL:EON22761.1};
OS Nocardioides sp. CF8.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=110319 {ECO:0000313|EMBL:EON22761.1, ECO:0000313|Proteomes:UP000015971};
RN [1] {ECO:0000313|EMBL:EON22761.1, ECO:0000313|Proteomes:UP000015971}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF8 {ECO:0000313|EMBL:EON22761.1,
RC ECO:0000313|Proteomes:UP000015971};
RX PubMed=23833136;
RA Kimbrel J.A., Chang J., Arp D.J., Sayavedra-Soto L.A.;
RT "The Draft Genome Sequence of Nocardioides sp. Strain CF8 Reveals the Scope
RT of Its Metabolic Capabilities.";
RL Genome Announc. 1:e00439-e00439(2013).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON22761.1}.
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DR EMBL; ASEP01000099; EON22761.1; -; Genomic_DNA.
DR AlphaFoldDB; R7XTZ5; -.
DR STRING; 110319.CF8_3352; -.
DR PATRIC; fig|110319.3.peg.4011; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_4_1_11; -.
DR Proteomes; UP000015971; Chromosome.
DR GO; GO:0003978; F:UDP-glucose 4-epimerase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013692; CapD_C.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF08485; Polysacc_syn_2C; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000015971}.
FT DOMAIN 2..275
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
FT DOMAIN 278..323
FT /note="UDP-glucose 4-epimerase CapD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08485"
SQ SEQUENCE 331 AA; 36633 MW; 570A5E2780325A3F CRC64;
MLVTGGTGSF GSTMVRRLLE TDVREVRIFS RDELKQDDMR RALNDSRVRF YIGDVRDYDS
VDRATRGVDF VFHAAALKQV PSCEFFPLEA VKTNVLGSSN VIEASNANGV SKVVCLGTDK
AVYPVNAMGI SKAMMEKTAQ AFARNNPTAN TVVSTVRYGN VMCSRGSVIP LFVEQLKAGK
PLTLTDPNMT RFLMSLDEAV YLVEHAFEHA TPGDLFVRKA PASTVAHLAQ AVAELVGVEA
QMDVIGTRHG EKLYETLATR EELSRAQEQD LYYRVPVDAR DLNYSQYFDE GDVAEATFDD
YHSHNTERLD VDGVKELLLS LPAFQGLLDK S
//
