ID   R7YIS9_CONA1            Unreviewed;       651 AA.
AC   R7YIS9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   13-SEP-2023, entry version 46.
DE   RecName: Full=Mif2/CENP-C cupin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=W97_01045 {ECO:0000313|EMBL:EON61827.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON61827.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CENP-C/MIF2 family.
CC       {ECO:0000256|ARBA:ARBA00010291}.
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DR   EMBL; JH767556; EON61827.1; -; Genomic_DNA.
DR   RefSeq; XP_007777144.1; XM_007778954.1.
DR   AlphaFoldDB; R7YIS9; -.
DR   STRING; 1168221.R7YIS9; -.
DR   GeneID; 19898356; -.
DR   eggNOG; ENOG502S47H; Eukaryota.
DR   HOGENOM; CLU_027966_0_0_1; -.
DR   OMA; CHGRVQV; -.
DR   OrthoDB; 2788001at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0000776; C:kinetochore; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0019237; F:centromeric DNA binding; IEA:InterPro.
DR   GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR028386; CENP-C/Mif2/cnp3.
DR   InterPro; IPR025974; Mif2/CENP-C_cupin.
DR   InterPro; IPR028929; Mif2_N.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   PANTHER; PTHR16684; CENTROMERE PROTEIN C; 1.
DR   PANTHER; PTHR16684:SF11; CENTROMERE PROTEIN C; 1.
DR   Pfam; PF11699; CENP-C_C; 1.
DR   Pfam; PF15624; Mif2_N; 1.
DR   SUPFAM; SSF51182; RmlC-like cupins; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT   DOMAIN          16..151
FT                   /note="Mif2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF15624"
FT   DOMAIN          586..651
FT                   /note="Mif2/CENP-C cupin"
FT                   /evidence="ECO:0000259|Pfam:PF11699"
FT   REGION          1..467
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        69..94
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..141
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        357..402
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..428
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        432..452
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   651 AA;  71138 MW;  E3E1209D8AD191CF CRC64;
     MAPASTPGRK KRENNFHDIG VQGRKTGITL KDTGIRDEHG FEPIEGMFSS PEKPSPRRTS
     RRTDVTLTSE EMEVQQSSMP EPTEALSARQ LLKGSSKTRF PPPVARSPIK TSLGSSPRRQ
     SSMGPPSQAR RSANTPGRAS SHPVVSRKLD FVADDTIESI EHSSPLQTNG IGSRGKAKAR
     QDIYDIQASP ERGQKRTFDE SIAEEEEEVE GVTDNPLDGT LDDEPVHMDG DDSLELLQAN
     GGADEDLVDE EPEVAPAVKT PTKRRGRPRR SDTSIIAAAA ETTNTKGKPG RKPAAGRPPK
     NRASLQSVSE PPEEPSVVPA QPKRRGRPPA AKKTADESLV NALLESGSGV DEPSVAEVAD
     PVKRKRGRQP AAEKQKKGSK VDVHRDNELD EASAEGPPAK RRKGAATKPP PSKRDPNAKI
     KSKKAMEKQQ SPVKGSVRSS SQQPSHVRSL QILRQGTPME DDGAKTTRFG RHVIKPLAHW
     RNERAEYTYD GGIQAIVRAE DIEPQKRTGN YSGVKRRPRA GKREMSVVKE EEEEELEAWE
     QAPGVIEGFV DGWDDTQDVA TEEQESQELA FAASALETRE VANANFQYAK ILSLPFFGIG
     MVDVPAGGFK RAKNTRRMQL AFFVHYGKVS VTVGENEFSI SKGGVWQVPR G
//