ID R7YK65_CONA1 Unreviewed; 748 AA.
AC R7YK65;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=W97_01494 {ECO:0000313|EMBL:EON62273.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON62273.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; JH767558; EON62273.1; -; Genomic_DNA.
DR RefSeq; XP_007777590.1; XM_007779400.1.
DR AlphaFoldDB; R7YK65; -.
DR STRING; 1168221.R7YK65; -.
DR GeneID; 19898805; -.
DR eggNOG; KOG2229; Eukaryota.
DR HOGENOM; CLU_009161_2_1_1; -.
DR OMA; AMYKTYK; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 69..438
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 547..674
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 697..742
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 465..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..541
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..597
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 671..710
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..734
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 84039 MW; 46437E23F09430D5 CRC64;
MVKRKVGALE KVDADLPNLQ YKIRRDPPSY ADDFGNQYRV YESFRELFLQ NPAQSDESGL
VSFRDQIDFI SHVADCYPKV TAEFPNDLIK IISQHHAELE PELREKIVGS LVLLRNKDII
DSSLLLGTLF PILVSTPSKS LRALLFTKIL SDLRSSNAKT TNHRLNRDVQ KELYNLLTSD
RSSSKGIWAV KITRELWKRQ IWTDSRAVEI MKEASLGDNE KVITSGVRFF LGGDKEREEA
AEESSDEEDT IDMRSLRHQA GINKKTRKKE KDLKKAAATV KRKERKKNVP HPLNFSALHL
LHDPQGFAEI LFSKHLQNSK SKLNLEQKLL VLNLVSRLVG LHKLTITSLY SYFTKYLTRR
QPSVTSFLAC LAQSTHNLVP PEDLEPLVRK ISDEFVTEAV AAEVCAAGLN AIREICVRQP
LAMNETLLQD LVMYRKSKDK GVMMAAKGLL SLYREVGAEM LKKRDRGKDA AMGLRSGEQK
AQRFGEEEAG GIEGLELLEK WKAEERRKKR VEQGLPPDAA TDEEVDEEDD KDWDVESDSD
SDDSGGWINV ESDGEDIEIS DSDDDERPTK KAKVDGTPSA GNGEQRESTQ EKAAVEAQRI
STLATTRILT PADLAKLNEL RMAQGINNLL PANKRRKAAE IARHADDAVT SEQIESAAAL
AKKTSKAEKI AMAKGDRDEK HHSTTAIRKS KKEAEGKSTT NKEKARKKNF LMTLGKAKSK
GKRSLVDTRK ALRGHIDRQK KGGRRGNR
//
