ID   R7YPK6_CONA1            Unreviewed;       709 AA.
AC   R7YPK6;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Spindle assembly checkpoint component MAD1 {ECO:0000256|ARBA:ARBA00022019};
GN   ORFNames=W97_03060 {ECO:0000313|EMBL:EON63832.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON63832.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the MAD1 family.
CC       {ECO:0000256|ARBA:ARBA00008029}.
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DR   EMBL; JH767565; EON63832.1; -; Genomic_DNA.
DR   RefSeq; XP_007779149.1; XM_007780959.1.
DR   AlphaFoldDB; R7YPK6; -.
DR   STRING; 1168221.R7YPK6; -.
DR   GeneID; 19900371; -.
DR   eggNOG; KOG4593; Eukaryota.
DR   HOGENOM; CLU_010064_1_0_1; -.
DR   OMA; YKLDFMP; -.
DR   OrthoDB; 2787310at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.30.457.60; -; 1.
DR   Gene3D; 6.10.250.90; -; 1.
DR   InterPro; IPR008672; Mad1.
DR   PANTHER; PTHR23168:SF0; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1; 1.
DR   PANTHER; PTHR23168; MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1; 1.
DR   Pfam; PF05557; MAD; 1.
DR   SUPFAM; SSF75704; Mitotic arrest deficient-like 1, Mad1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          449..488
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          101..295
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        463..488
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   709 AA;  80906 MW;  37BA48B7AC6BF594 CRC64;
     MAAARNQPTY DFLTGASSPP PAPTFRDSLR APSAVRSDAS NEPLRAQLRT LQYELDSLKQ
     DRDLTALQHQ KELRDVQTKA EADFRRAQLA EASSHAAVAK YDALARELQE TQDRCANERL
     ELERRGRTLQ EENRALREEV EDVRSELLAQ ERGSKRRVEE LETRHTALQA SFEAMKEDSE
     GKVEALAETQ QRLVQREAEN AQLESEVLRL KAQDGESETL AVVKRQLSEQ VAHIRKLEST
     NREQIAELRQ YRKSQKSIEV VEEEKRVLES RVRMMDDLRK QLSEAQLQRQ ILEDERKSWT
     TYLQTESSAE GELHFESPEE LARAFIQERL ETASLLERLG ALQPELSVKD DNIQTLEDEK
     AKLQAELEKL RSTGGGADSK VRARLERQRA LAVKEVEYLR EQLKIFDTEE SEFKPESFDE
     QKSARIRELE DMVDAYRKEV QTLQSELSTV TEELAKKQQQ DPTTTGSKRR RDSDSDTNER
     LGELRRKNRQ LQDTISALQT RNALLDKELA ALQSQLSSLK SASRTRILEL RSNPTANAEA
     LKASTLNALR EENRALLSQL ENRHSGQPDD TPLVPAATLT VLRNELSAMA LEVASKEKRM
     LRLKQIWSAK SAEFREAVAS ILGYKMDFMP NGRVRVTSVF YPGEEEGENS IVFDGENGTM
     KVSGGPKSEF AGEIRELIEF WVEGRKDIPC FLAAMTLEFY ERFTRVPKG
//