ID R7YYY5_CONA1 Unreviewed; 1001 AA.
AC R7YYY5;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=W97_06294 {ECO:0000313|EMBL:EON66891.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON66891.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JH767583; EON66891.1; -; Genomic_DNA.
DR RefSeq; XP_007782208.1; XM_007784018.1.
DR AlphaFoldDB; R7YYY5; -.
DR STRING; 1168221.R7YYY5; -.
DR GeneID; 19903605; -.
DR eggNOG; KOG3519; Eukaryota.
DR HOGENOM; CLU_007879_1_0_1; -.
DR OMA; EVENIMP; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00666; PB1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS51745; PB1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT DOMAIN 224..404
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 905..1001
FT /note="PB1"
FT /evidence="ECO:0000259|PROSITE:PS51745"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 806..826
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..604
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..637
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1001 AA; 112072 MW; 68FE0534603B0886 CRC64;
MHNHGHQSYG SSSYSTSSHP SFRDSDSTQG TSQSTLFPPP TPTPSLTPTP SNGGPVEAAN
NVINKRADKE TSLFQICLNL RQRLRGVPDF EQSMLEEEMI ADEGVDPVTL LWRTFRQGFP
LLKIYNALNP RIPLAVDPKV PEKKRGQTAT YKFIQGCLTE LRFPSDECFI LTDLYGDDTT
GFVKVAKVVN RVLDILVQAG LLSAQVENQD ASLENGIGGG KRTQREHIIE ELVKTERTYV
QHLELLQAFK KLVEEKGVIT GDAVHDIFLN LNALLDFQRR FLIRVEQINS EPESNQNWGK
LFILYRDAFK VYEPYIANQK KCEEVAMREF DKLKETGGPL ELRQMAETPA NLISFLLKPF
QRLTKYPLLL KQLRDRGGLD EERKADISTG IEAASEVLER TNAAVDREER QAAVEELGGR
VEDWKGHKIE GFGDLLLHGT FTVLKGDTKD QEREYRIYLF EMILLCCKEM NPNKQKNKLM
NKPLVDKRGK PKLQLKGRIF MQNVTDLISF GKPGSYTCQI FWKGDPGIEN FVIRFTTEET
MKKWAHQVDL QRRLFKDIAR TSNGTTKASS TSTTEFTYMR GQEPIENPYR QEDEGEDDDD
DTLVDGYPGG VHYASTQNGS SASLRSRSAT NDSGPLAMPQ SDPRAPPPRF PMGFTGQPAL
TLRTQQLQQN GHTPGDAQMD SYFSPGVDSP TSSRTSSSSG MFPFPRQPAP TNGWHGEEHA
RYTAPAMARN VSRDGSTYPI NGRNPMQRPA IPAPNSFQQN RLRSASSPDI QNSLRRMQTG
PQPPVPDLPP FPTHYAYAPN ISSINRSQNN SPGIPTSLPT RAATQSPAIQ RERLMLQRGA
TEHPDMYQVG DSHHPRHGPM PRTLTPASSL EHARAMTPGP IEPRTISPPL SITPRPAEEV
QIPSQLKVKV HCPSAGSTMT LVVSTNISYQ SLKDRIDAKL QRSTKVSLSS GQVKLKYNDD
GDFVNIQSDE DVQTAFETWK EQQKDQIVAG SMGEIELYCQ R
//
