ID R7Z0T7_CONA1 Unreviewed; 867 AA.
AC R7Z0T7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=alpha-glucosidase {ECO:0000256|ARBA:ARBA00012741};
DE EC=3.2.1.20 {ECO:0000256|ARBA:ARBA00012741};
GN ORFNames=W97_06831 {ECO:0000313|EMBL:EON67688.1};
OS Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetes incertae sedis; Coniosporium.
OX NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON67688.1, ECO:0000313|Proteomes:UP000016924};
RN [1] {ECO:0000313|Proteomes:UP000016924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Coniosporium apollinis CBS 100218.";
RL Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-
CC glucose residues with release of alpha-D-glucose.; EC=3.2.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00001657};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 31 family.
CC {ECO:0000256|ARBA:ARBA00007806, ECO:0000256|RuleBase:RU361185}.
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DR EMBL; JH767589; EON67688.1; -; Genomic_DNA.
DR RefSeq; XP_007783005.1; XM_007784815.1.
DR AlphaFoldDB; R7Z0T7; -.
DR STRING; 1168221.R7Z0T7; -.
DR GeneID; 19904142; -.
DR eggNOG; KOG1066; Eukaryota.
DR HOGENOM; CLU_000631_9_0_1; -.
DR OMA; FGYDVYR; -.
DR OrthoDB; 5488985at2759; -.
DR Proteomes; UP000016924; Unassembled WGS sequence.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd14752; GH31_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1760; glycosyl hydrolase (family 31); 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR048395; Glyco_hydro_31_C.
DR InterPro; IPR025887; Glyco_hydro_31_N_dom.
DR InterPro; IPR000322; Glyco_hydro_31_TIM.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR22762; ALPHA-GLUCOSIDASE; 1.
DR PANTHER; PTHR22762:SF165; PUTATIVE (AFU_ORTHOLOGUE AFUA_1G06560)-RELATED; 1.
DR Pfam; PF13802; Gal_mutarotas_2; 1.
DR Pfam; PF01055; Glyco_hydro_31_2nd; 1.
DR Pfam; PF21365; Glyco_hydro_31_3rd; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361185};
KW Hydrolase {ECO:0000256|RuleBase:RU361185};
KW Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT DOMAIN 40..205
FT /note="Glycoside hydrolase family 31 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13802"
FT DOMAIN 257..612
FT /note="Glycoside hydrolase family 31 TIM barrel"
FT /evidence="ECO:0000259|Pfam:PF01055"
FT DOMAIN 622..719
FT /note="Glycosyl hydrolase family 31 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21365"
SQ SEQUENCE 867 AA; 96379 MW; E19608AD1AD543E1 CRC64;
MAPQHEFVPQ TYAIDSSKNP SSKASLYLRS QDKQGLPADF SFEAIRSNVF RTRFTTKDHP
LPPHPSAPLP EIRHGDVVPA TTLSKSSYQT KIGDVVAEVD FTGCPQVSLS FADSEAPLHA
DLPYRSYATD GTGVAHYTKY KRGTLHVGLG EKAAPMDLSN RQFVLSATDC FGYDVYRTDP
MYKHIPLLIN ATPEGCVGVF STSHARGFYS VGSEMDGMWG YYKVYRQDHG GLEEYLIISR
TLKELVRTYA DLVGYPLLVP RWAFGYLAGG MKYSMLDEPR ACDALIDFAK KMKEEDIPCS
GFQMSSGYTV AETEPKTRNV FTWNRHRFPD PKAFIDEYHK QGIRLIFNVK PYVLANHPEY
EKLSKNGALI KDLRTGKSGT ARLWSAGGGE SGEGGHIDFT SKAGFQWWYN GIRDLKKLGV
DCIWNDNNEY TIPDDHWQCE LDEPSVQGSD EAKQLKHIGY WGRALQTELM AKSSHDATVE
VEPELRPFIL TRSATAGSMR YCASSWSGDN VTSYDGMKGA NALALTAGMC LLQCYGHDIG
GFEGPQPSPE LLVRWVQLGI YSSRFAINCF KTTPTNNNLG EVIEPWMYPE ATPLVRAAIK
RRYEMIPYIY SLALESHAAA SPPQRWTGWG YEADPMVWEN RMIKNGETQF WLGDSLLVGG
VFEPGETKAK MYLPRKSAYD PGFLNLNAPF QFFAAGQWVE IDSKWDASIP VLARIGAAIP
VGKDVQTLSA GETVNPASLP KDDYRAVEIF PPPLSAGTTG TFETTWLEDD GVSPTAEPVE
FRLSYRCLDA LVEVELSRSG SDVQLAWREE DLSVILPVGD AHEEVTLNGK KLSCSRTDQR
GRKVFCSSTV MNGVKEVNGM NGINGHH
//
