ID   R7Z6Y5_CONA1            Unreviewed;      1069 AA.
AC   R7Z6Y5;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   RecName: Full=tRNA/rRNA methyltransferase SpoU type domain-containing protein {ECO:0000259|Pfam:PF00588};
GN   ORFNames=W97_09037 {ECO:0000313|EMBL:EON69774.1};
OS   Coniosporium apollinis (strain CBS 100218) (Rock-inhabiting black yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetes incertae sedis; Coniosporium.
OX   NCBI_TaxID=1168221 {ECO:0000313|EMBL:EON69774.1, ECO:0000313|Proteomes:UP000016924};
RN   [1] {ECO:0000313|Proteomes:UP000016924}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 100218 {ECO:0000313|Proteomes:UP000016924};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Gorbushina A., Noack S., Walker B., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The genome sequence of Coniosporium apollinis CBS 100218.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; JH767628; EON69774.1; -; Genomic_DNA.
DR   RefSeq; XP_007785091.1; XM_007786901.1.
DR   AlphaFoldDB; R7Z6Y5; -.
DR   STRING; 1168221.R7Z6Y5; -.
DR   GeneID; 19906348; -.
DR   eggNOG; KOG0839; Eukaryota.
DR   HOGENOM; CLU_005519_0_0_1; -.
DR   OMA; ADQRKYC; -.
DR   OrthoDB; 7433at2759; -.
DR   Proteomes; UP000016924; Unassembled WGS sequence.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IEA:InterPro.
DR   GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR   CDD; cd18091; SpoU-like_TRM3-like; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR045330; Trm3/TARBP1.
DR   InterPro; IPR044748; Trm3/TARBP1_C.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR12029:SF11; METHYLTRANSFERASE TARBP1-RELATED; 1.
DR   PANTHER; PTHR12029; RNA METHYLTRANSFERASE; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016924}.
FT   DOMAIN          911..1057
FT                   /note="tRNA/rRNA methyltransferase SpoU type"
FT                   /evidence="ECO:0000259|Pfam:PF00588"
FT   REGION          820..904
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        850..904
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1069 AA;  119197 MW;  D54681AAC0A9A88D CRC64;
     MNDKYWELLQ EGLRTGYSEQ RKYCLSILKT SVQILNIDLD APHMTLQIRA KMDYVLHFDK
     YITVFETIVL GRYMNQVEEC LPDLQMLCSS SSRIHPTWMK TLLEAAFQQN IQDGIRKFVG
     NWLMDLSSLY LDLDRPTQEG GHRLLITLIT QTSPKNNIIT QSLLPWATQG SLFTSSIRST
     QDNRTVCCEH GEKLSSFIEG LLRRCPDNTI RSLHLRTLLT WLHDTSIDGR LFPHAAAYIV
     DGLVRGAGLQ EPICRIGKGA PLDVVVPGIE QQDLELLVKI ATRTGLPEVV RDYLVALCLR
     IESLLKRTSP GSAMEGFTYT TMLARHTWLL APVTIEKLTA LELQKWLVHA AIEASGPSAS
     ANNHYDEDEK GKIIVDLGSR NLSLTEFIKP LVLTNYELLH GSGLNRSCRY LFLLLNNNSS
     DTVPSNLLLQ ALEAIWSEVE RQDYPKQSLM EVPNVFFHPT SIKLSVDAPE LAALLSSTLA
     ILQQLCDGRI YVFSPLAKAL SNAYRKAPEV TKLLPFEDFI VQIANHPPSP KLEFLLDSSV
     AEKLEQIAPH RTYSFYYGHH QSYGYACIFD TLNSLRVTDH AVGKRIFDRL LEPWANQKMP
     ISIVSKWKKT TQLQTMLLLL DTCMSTSTSE ELSAYLRSLL SIISIEPLPR YRFLLEWIIA
     RIYVQHPDRR PDLLTLISTK DHSNPKYLAS IMKLAVMIAR VADSPESFAL KLMTQLVPLS
     ASSKIIIRHE AQWSFPPLWD HAAERDWTSI TENPAFAALN DSIRSHEKYL APPPGRSLEW
     LDPVDDHNLA TLFQGGYLRM EPAEGEIVRV EDFEELWAEK ENTRSGEGAE KAMPPPRVPL
     GRRKPQAPST PAAAQETESQ DTIAHAPSLL SPATATTPTP LQTKPQTLPL LSPSRPLSTD
     PLDPSTRPTP LIIIASLIAN PHNLGGLSRI SEIFGAASLH LRTTAVLTDR DFLAVSVSSH
     LHLSIHALPP TPSSLLPFLR ERKGEGYTVV GIEQTDASFV LGAPGTSVPR KAVLVLGSER
     EGIPGWLLSE MDACVEIGQV GRTRSLNVQT AAGCVLFEWW REHGGGGGG
//