ID R7ZIL1_LYSSH Unreviewed; 305 AA.
AC R7ZIL1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:EON73896.1};
GN ORFNames=H131_04504 {ECO:0000313|EMBL:EON73896.1};
OS Lysinibacillus sphaericus OT4b.31.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX NCBI_TaxID=1285586 {ECO:0000313|EMBL:EON73896.1, ECO:0000313|Proteomes:UP000013911};
RN [1] {ECO:0000313|EMBL:EON73896.1, ECO:0000313|Proteomes:UP000013911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT4b.31 {ECO:0000313|EMBL:EON73896.1,
RC ECO:0000313|Proteomes:UP000013911};
RA Pena-Montenegro T.D., Dussan J.;
RT "Draft genome of the heavy metal tolerant bacterium Lysinibacillus
RT sphaericus strain OT4b.31.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON73896.1}.
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DR EMBL; AQPX01000008; EON73896.1; -; Genomic_DNA.
DR RefSeq; WP_010857865.1; NZ_KB933398.1.
DR AlphaFoldDB; R7ZIL1; -.
DR PATRIC; fig|1285586.5.peg.913; -.
DR eggNOG; COG0119; Bacteria.
DR HOGENOM; CLU_022138_3_2_9; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000013911; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EON73896.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT DOMAIN 7..274
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 305 AA; 33401 MW; 86F1FCA17613D2DA CRC64;
MQLPKHVTLK EVGPRDGLQN EKIHIATADK IQLVNLLSQT GLNYIEVTSF VHPKWIPQLA
DAVEVLQAIK REKDITYAAL VPNMRGLERA LQADIDEVNV FMSASESHNQ NNINKTIAET
FPILQEVVTA AKAEHKSVRG YISTVIGCPY EGYIQPEKVL RVTDKLLEMG VDEISLGDTI
GVGVPTQVES LLEELFKRYP AQKFAMHFHD TRGTALVNIM KSLEMGITKF DSALGGLGGC
PYAKGASGNI ATEDVLYLLD GMDIKTGVDM SSLLKAAYFI EQKLGKSVAS KQMAIVRNEG
SANVL
//
