ID R7ZQ31_9BACT Unreviewed; 406 AA.
AC R7ZQ31;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=alanine dehydrogenase {ECO:0000256|ARBA:ARBA00012897};
DE EC=1.4.1.1 {ECO:0000256|ARBA:ARBA00012897};
GN ORFNames=ADIS_3369 {ECO:0000313|EMBL:EON76241.1};
OS Lunatimonas lonarensis.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae.
OX NCBI_TaxID=1232681 {ECO:0000313|EMBL:EON76241.1, ECO:0000313|Proteomes:UP000013909};
RN [1] {ECO:0000313|EMBL:EON76241.1, ECO:0000313|Proteomes:UP000013909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK24 {ECO:0000313|EMBL:EON76241.1,
RC ECO:0000313|Proteomes:UP000013909};
RA Singh A.;
RT "A novel strain isolated from Lonar lake, Maharashtra, India.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AlaDH/PNT family.
CC {ECO:0000256|ARBA:ARBA00005689}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EON76241.1}.
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DR EMBL; AQHR01000088; EON76241.1; -; Genomic_DNA.
DR RefSeq; WP_010855502.1; NZ_AQHR01000088.1.
DR AlphaFoldDB; R7ZQ31; -.
DR STRING; 1232681.ADIS_3369; -.
DR PATRIC; fig|1288963.3.peg.3362; -.
DR OrthoDB; 9804592at2; -.
DR Proteomes; UP000013909; Unassembled WGS sequence.
DR GO; GO:0000286; F:alanine dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0042853; P:L-alanine catabolic process; IEA:InterPro.
DR CDD; cd05305; L-AlaDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008141; Ala_DH.
DR InterPro; IPR007886; AlaDH/PNT_N.
DR InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR42795; ALANINE DEHYDROGENASE; 1.
DR PANTHER; PTHR42795:SF1; ALANINE DEHYDROGENASE 1; 1.
DR Pfam; PF01262; AlaDh_PNT_C; 1.
DR Pfam; PF05222; AlaDh_PNT_N; 1.
DR SMART; SM01002; AlaDh_PNT_C; 1.
DR SMART; SM01003; AlaDh_PNT_N; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EON76241.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000013909}.
FT DOMAIN 35..168
FT /note="Alanine dehydrogenase/pyridine nucleotide
FT transhydrogenase N-terminal"
FT /evidence="ECO:0000259|SMART:SM01003"
FT DOMAIN 180..328
FT /note="Alanine dehydrogenase/pyridine nucleotide
FT transhydrogenase NAD(H)-binding"
FT /evidence="ECO:0000259|SMART:SM01002"
SQ SEQUENCE 406 AA; 43937 MW; 5B2C75B90D2BEFF9 CRC64;
MPSQIELAEI AVKAGAIPKE SLARIGKAKK KIIIGVPKED ANQEKRVLLT PEAVGLLINN
GQQVIVESNA GVAAKFSDKA YLDAGAKVVS SKEEAYDAEV VLRVDPPSVQ EIGFMRQGAC
LLSSLQIRNQ TAEFIQALNQ KKITAVAFEY LEDKVGGMPV VRAMSEIAGS TVMLIAAEYL
SSVNGGKGLI LGGITGVPPT QVVIIGAGTV AEYAARTALG LGANIKIFDN QLYKLRRIKQ
LLGQQVFTST IDNFTLCQAL READVVIGAL RAERGRAKMV VTEEMVAQMM DGSIIIDVSI
DQGGCIETAE ATTHDNPVYT KHNIVHYCVP NIASRVARTA SFSFSNIFTP MLLQMADLGG
AEEMIFNYKW FMKGVYGYRG SLTNAYLARK FGMPHKELQL LLAARY
//
