ID   R7ZXA9_9BACT            Unreviewed;       548 AA.
AC   R7ZXA9;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Alkaline phosphatase {ECO:0000313|EMBL:EON78805.1};
DE            EC=3.1.3.1 {ECO:0000313|EMBL:EON78805.1};
GN   ORFNames=ADIS_0702 {ECO:0000313|EMBL:EON78805.1};
OS   Lunatimonas lonarensis.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cyclobacteriaceae.
OX   NCBI_TaxID=1232681 {ECO:0000313|EMBL:EON78805.1, ECO:0000313|Proteomes:UP000013909};
RN   [1] {ECO:0000313|EMBL:EON78805.1, ECO:0000313|Proteomes:UP000013909}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AK24 {ECO:0000313|EMBL:EON78805.1,
RC   ECO:0000313|Proteomes:UP000013909};
RA   Singh A.;
RT   "A novel strain isolated from Lonar lake, Maharashtra, India.";
RL   Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EON78805.1}.
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DR   EMBL; AQHR01000022; EON78805.1; -; Genomic_DNA.
DR   RefSeq; WP_010852850.1; NZ_AQHR01000022.1.
DR   AlphaFoldDB; R7ZXA9; -.
DR   STRING; 1232681.ADIS_0702; -.
DR   PATRIC; fig|1288963.3.peg.699; -.
DR   OrthoDB; 9766127at2; -.
DR   Proteomes; UP000013909; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:UniProtKB-EC.
DR   CDD; cd16016; AP-SPAP; 1.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   PANTHER; PTHR10151:SF126; PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EON78805.1};
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000013909};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..548
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004462026"
FT   ACT_SITE        81
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         102
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         163..165
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   548 AA;  61296 MW;  61E18B4302A9C423 CRC64;
     MTKNIYCLFL ALLPFVASAQ TSEPSHEITR PKLVVGIVVD QMRQEYFYKF HDRYVDGGFK
     RLMHEGFMMK NGHYNYIPTY TGPGHASVYT GATPATHGII ANDWYVRQLG RTVYCAEDST
     VSYVGGSESA GKISPRNMLT TTITDELRFA TNKRSKVVAI SLKDRGAALP AGHLGTAYWY
     DGKTGEFMNS SYYGEKLPAW VVDFNKRQLP QNYLRQTWEP LFPLASYLQS VSDDNEFEAV
     PIGKDAPVFP YVLPELMQNN GGLGMISSTP FGNSLTLDMA YAALESEELG RRGETDFLAI
     SFSATDYVGH AFGPSSIELE DTYLRLDREL AAFFAHLDRE IGVGEYLVFL SADHGVADVV
     RFMQSENVPA GSLNTRFVLT QLRGYTTQKY GEGNWIENFS NEQVFLNHQL IREKGIDLHA
     MQEDVAAFLL RFEGIKETYT AQDMRRHEFT LGRRHLLQMG FNHKASGDVL LVLDAAWLTD
     ASRGTTHGTG YTYDTHVPIV FYGWGIKPGS SSRYANVTDI APTLAMLLHT RLPNGATGQP
     IGEILDRE
//