ID R8I048_BACCE Unreviewed; 794 AA.
AC R8I048;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 52.
DE SubName: Full=DNA translocase ftsK {ECO:0000313|EMBL:EOO78367.1};
GN ORFNames=IIC_00728 {ECO:0000313|EMBL:EOO78367.1};
OS Bacillus cereus VD021.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=1053224 {ECO:0000313|EMBL:EOO78367.1, ECO:0000313|Proteomes:UP000014040};
RN [1] {ECO:0000313|EMBL:EOO78367.1, ECO:0000313|Proteomes:UP000014040}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VD021 {ECO:0000313|EMBL:EOO78367.1,
RC ECO:0000313|Proteomes:UP000014040};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Van der Auwera G.A., Mahillon J., Duprez V., Timmery S.,
RA Mattelet C., Dierick K., Sun M., Yu Z., Zhu L., Hu X., Shank E.B.,
RA Swiecicka I., Hansen B.M., Andrup L., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacillus cereus VD021.";
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the FtsK/SpoIIIE/SftA family.
CC {ECO:0000256|ARBA:ARBA00006474}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOO78367.1}.
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DR EMBL; AHES01000004; EOO78367.1; -; Genomic_DNA.
DR RefSeq; WP_002014584.1; NZ_KB976273.1.
DR AlphaFoldDB; R8I048; -.
DR GeneID; 66266641; -.
DR PATRIC; fig|1053224.3.peg.731; -.
DR HOGENOM; CLU_001981_9_6_9; -.
DR Proteomes; UP000014040; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.30.980.40; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041027; FtsK_alpha.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR018541; Ftsk_gamma.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR22683:SF41; DNA TRANSLOCASE FTSK; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF17854; FtsK_alpha; 1.
DR Pfam; PF09397; FtsK_gamma; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00843; Ftsk_gamma; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 459..655
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 215..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 476..483
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 794 AA; 88303 MW; 75C23CDB06BBF125 CRC64;
MAKQKQRGTK AKARRTIKPT LYYEIVGLTL FALSIITILQ LGVVGKSFVL FFRFFFGEWY
IIGVLGVIAL SVAFVIKRGW PNLLNKRLIG VYLIVLAILM FSHITLFNLL TKDGAVQNTS
VIVSTKDYFF LEMKKGPDSV HLGGGMFGAL MFATCYFLFD EVGAYIIGII LVILGILCIT
NKHIGEVLAP VGRILRSQFQ VMQGDYKDWK SQRVAEQTEK KKTTRSKRRE RVAEQEEAIE
PVEEIEIGPP IISNFTENYP VREETEKQIE ENDLITPPFI EEAVPPAPEE QPHKKRGEKI
VESLEGETKA PPMQFSNVEN KDYKLPSLDI LKFPQNKQVT NENAEIYENA RKLERTFQSF
GVKAKVTKVH RGPAVTKYEV YPDMGVKVSK IVSLSDDLAL ALAAKDIRIE APIPGKSAVG
IEVPNSEVSM VTLREVLDSK ANNHPEEKLL IGLGRDVTGE AVLARLNKMP HLLVAGATGS
GKSVCINGII VSILMRAKPH EVKLMMIDPK MVELNVYNGV PHLLTPVVTD PKKASQALKK
VVSEMERRYE LFAHSGTRNI EGYNDYIKEH NSQSEAKQPE LPYIVVIVDE LADLMMVASS
DVEDAIMRLA QMARAAGIHL IIATQRPSVD VITGVIKANI PSRIAFAVSS QIDSRTILDG
GGAEKLLGRG DMLFIPIGAS KPVRVQGAFL SDDEVERVVE SVIAQQKAQY QEDMIPQDVP
ETKQEVEDEL YDEAVQLVVE MQTASVSMLQ RRFRVGYTRA ARLIDAMEMN GVVGPYEGSK
PRGVLIKDVQ EKSS
//
