ID   R9CF38_9CLOT            Unreviewed;       300 AA.
AC   R9CF38;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   SubName: Full=TrmH family RNA methyltransferase {ECO:0000313|EMBL:EOR27902.1};
GN   ORFNames=A500_02073 {ECO:0000313|EMBL:EOR27902.1};
OS   Clostridium sartagoforme AAU1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=1202534 {ECO:0000313|EMBL:EOR27902.1, ECO:0000313|Proteomes:UP000013988};
RN   [1] {ECO:0000313|EMBL:EOR27902.1, ECO:0000313|Proteomes:UP000013988}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAU1 {ECO:0000313|EMBL:EOR27902.1,
RC   ECO:0000313|Proteomes:UP000013988};
RA   Joshi C.G., Duggirala S.M., Nathani N.M., Bhatt V.D., Patel A.K.,
RA   Pandya P.R., KaPatel J.A.;
RT   "Whole genome shotgun sequencing of Clostridium sartagoforme AAU1.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOR27902.1}.
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DR   EMBL; ASRV01000024; EOR27902.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9CF38; -.
DR   PATRIC; fig|1202534.3.peg.418; -.
DR   Proteomes; UP000013988; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd18103; SpoU-like_RlmB; 1.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR   InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR   PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR   PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF75217; alpha/beta knot; 1.
DR   SUPFAM; SSF55315; L30e-like; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000313|EMBL:EOR27902.1};
KW   Transferase {ECO:0000313|EMBL:EOR27902.1}.
FT   DOMAIN          58..133
FT                   /note="RNA 2-O ribose methyltransferase substrate binding"
FT                   /evidence="ECO:0000259|SMART:SM00967"
FT   REGION          19..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..49
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   300 AA;  33436 MW;  0DC8A2702795496B CRC64;
     MTKGNREARM KARMERQMFE NASAQGKRQF TRENKNARDN YSKESVVTQN EEETREDLII
     GRNAVIEVLK SDRTIECIYI ANGNMEGSIK VIINMAREKG LVLKEVDRKK LDGMSNGTNH
     QGVIALVTPF KYCQIADMLK DAREKKQDPF IVILDEIEDP HNLGSIIRTA ELCGVHGIII
     PKRRNVGITS TVYKCSVGAI EHMKIAKVTN INAAIDELKE SGIWVYGADI AGEEYSYEVN
     FNGPCAVVIG SEGRGISKLT LKKCDKLIKI PMIGKINSLN ASVAGGIMMY EILKGRLLKK
//