ID R9GRF6_9SPHI Unreviewed; 383 AA.
AC R9GRF6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Homocitrate synthase {ECO:0000313|EMBL:EOR94273.1};
DE EC=2.3.3.14 {ECO:0000313|EMBL:EOR94273.1};
GN ORFNames=ADIARSV_2514 {ECO:0000313|EMBL:EOR94273.1};
OS Arcticibacter svalbardensis MN12-7.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Arcticibacter.
OX NCBI_TaxID=1150600 {ECO:0000313|EMBL:EOR94273.1, ECO:0000313|Proteomes:UP000014174};
RN [1] {ECO:0000313|EMBL:EOR94273.1, ECO:0000313|Proteomes:UP000014174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MN12-7 {ECO:0000313|EMBL:EOR94273.1,
RC ECO:0000313|Proteomes:UP000014174};
RX PubMed=23846277;
RA Shivaji S., Ara S., Prasad S., Manasa B.P., Begum Z., Singh A.,
RA Kumar Pinnaka A.;
RT "Draft Genome Sequence of Arcticibacter svalbardensis Strain MN12-7T, a
RT Member of the Family Sphingobacteriaceae Isolated from an Arctic Soil
RT Sample.";
RL Genome Announc. 1:E00484-13(2013).
CC -!- SIMILARITY: Belongs to the alpha-IPM synthase/homocitrate synthase
CC family. {ECO:0000256|RuleBase:RU003523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOR94273.1}.
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DR EMBL; AQPN01000090; EOR94273.1; -; Genomic_DNA.
DR RefSeq; WP_016195745.1; NZ_AQPN01000090.1.
DR AlphaFoldDB; R9GRF6; -.
DR STRING; 1150600.ADIARSV_2514; -.
DR PATRIC; fig|1150600.3.peg.2487; -.
DR eggNOG; COG0119; Bacteria.
DR OrthoDB; 9804858at2; -.
DR Proteomes; UP000014174; Unassembled WGS sequence.
DR GO; GO:0004410; F:homocitrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd07939; DRE_TIM_NifV; 1.
DR Gene3D; 1.10.238.260; -; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR002034; AIPM/Hcit_synth_CS.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR013477; NifV/FrbC.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42880; HOMOCITRATE SYNTHASE; 1.
DR PANTHER; PTHR42880:SF1; ISOPROPYLMALATE_HOMOCITRATE_CITRAMALATE SYNTHASE FAMILY PROTEIN; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00815; AIPM_HOMOCIT_SYNTH_1; 1.
DR PROSITE; PS00816; AIPM_HOMOCIT_SYNTH_2; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:EOR94273.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000014174};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003523}.
FT DOMAIN 10..261
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 383 AA; 41809 MW; 7E9B050C9A836F08 CRC64;
MGNDRGIFNT LLIDTTLRDG EQAPGVVFDL NDKIRIACLL EQAGIKEVEL GTPVMGSREV
NDIKTIVELG LNFRSTAWCR ANRLDLDAAL KTGVNSVNIS FPVSPILLKA LGKNYHWVIE
NLRDLVRYAS DHFEYIAIGA QDASRAEFSF LSYFLAEANR VGASRLRIAD TVGLLTPLST
MELFTKVRKI LPDVSLEFHG HNDLGMATAN TLTALQTGAD AASLTVNGLG ERAGNAALEE
LVMALDLGGK MEHGIHTEVL NELCMEVSKA SGIPIHDHKA ITGSKVLSHE SGIHTSCLLA
NRETYQIIDP EKIGRPQGEF VFGKHSGTAA LISFLNSKAI AINKAESVSL LHVIKEMSCR
LKRSLSQLEV QNLYLNKEYV INS
//
