ID R9I5C9_BACUN Unreviewed; 646 AA.
AC R9I5C9;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Glycoside hydrolase {ECO:0008006|Google:ProtNLM};
GN ORFNames=C801_01774 {ECO:0000313|EMBL:EOS08570.1};
OS Bacteroides uniformis dnLKV2.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=1235787 {ECO:0000313|EMBL:EOS08570.1, ECO:0000313|Proteomes:UP000014212};
RN [1] {ECO:0000313|EMBL:EOS08570.1, ECO:0000313|Proteomes:UP000014212}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=dnLKV2 {ECO:0000313|Proteomes:UP000014212};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Kuhn K., Stappenbeck T., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides uniformis dnLKV2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS08570.1}.
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DR EMBL; ASSO01000007; EOS08570.1; -; Genomic_DNA.
DR RefSeq; WP_016273055.1; NZ_KE159485.1.
DR AlphaFoldDB; R9I5C9; -.
DR PATRIC; fig|1235787.3.peg.1797; -.
DR HOGENOM; CLU_010779_2_0_10; -.
DR Proteomes; UP000014212; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR CDD; cd08983; GH43_Bt3655-like; 1.
DR CDD; cd18828; GH43_BT3675-like; 1.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR43772:SF2; BETA-1,4-XYLOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR43772; ENDO-1,4-BETA-XYLANASE; 1.
DR Pfam; PF04616; Glyco_hydro_43; 2.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00022651};
KW Reference proteome {ECO:0000313|Proteomes:UP000014212};
KW Signal {ECO:0000256|SAM:SignalP};
KW Xylan degradation {ECO:0000256|ARBA:ARBA00022651}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..646
FT /note="Glycoside hydrolase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004474217"
FT ACT_SITE 351
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 531
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 476
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 646 AA; 72813 MW; BAD874100132DEC7 CRC64;
MIVRMKNTFR MLLAAMLLSL FALPGYSWQK SFPEKDYVAY LFTYFTGNSG DEEAVRYAVS
MDGYTYWALN DNEPVIDSKV ISSTGGVRDP HILRCEDGKT FYMVVTDMVS ANGWSSNRAM
VLLKSTDLVN WSHSVINIQK RYSGQEDLKR VWAPQTIYDP EAGKYMVYWS MLHGDGADVI
YYAYANAEFT DLEGEPKPLF LPENGKSCID GDIVYKDGVF HLFYKTEGHG NGIKVATTRS
LTSGAWTEEP DYKQQTKEAV EGAGTFKLIG QDKYILMYDV YMKGSYQFTE TTDLKNFKVI
DSEVKMNFHP RHGTIIPITR HELLRITDEW GKPTELGALP NNPVLPGFHA DPEILYSHQT
QKYYIYSTTD GQPGWGGWYF TVFSSTDLKT WQDEGVMLDL QSEQVPWADG NAWAPCIEEK
KVDGKYKYFF YYSGNPKNGG GKQIGVATSD SPAGPFTDLG RPVVTASPVG GGQQIDVDVF
TDPVSGKSYL YWGNGYMAGA ELNDDMVSIK ENTVTVMTPA GGTLQDYAFR EAAYVFYRNG
LYYFMWSVDD TGSPNYHVAY GTSKSPLGPI EVAKQPVVLI QNPEKEIYGP AHNAVLQIPG
TDEWRIVYHR INKWYLKDGP GVHREVCIDR MEFNEDGTIR PVVPTF
//
