ID R9J4J7_9FIRM Unreviewed; 437 AA.
AC R9J4J7;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN ORFNames=C807_03031 {ECO:0000313|EMBL:EOS29140.1};
OS Lachnospiraceae bacterium 28-4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=397287 {ECO:0000313|EMBL:EOS29140.1, ECO:0000313|Proteomes:UP000014112};
RN [1] {ECO:0000313|EMBL:EOS29140.1, ECO:0000313|Proteomes:UP000014112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-4 {ECO:0000313|EMBL:EOS29140.1,
RC ECO:0000313|Proteomes:UP000014112};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 28-4.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS29140.1}.
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DR EMBL; ASSU01000027; EOS29140.1; -; Genomic_DNA.
DR AlphaFoldDB; R9J4J7; -.
DR PATRIC; fig|397287.3.peg.3331; -.
DR eggNOG; COG2826; Bacteria.
DR HOGENOM; CLU_046274_0_0_9; -.
DR OrthoDB; 9776104at2; -.
DR Proteomes; UP000014112; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR025246; IS30-like_HTH.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; NF033563; transpos_IS30; 1.
DR PANTHER; PTHR10948; TRANSPOSASE; 1.
DR PANTHER; PTHR10948:SF23; TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED; 1.
DR Pfam; PF13936; HTH_38; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014112}.
FT DOMAIN 245..408
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
SQ SEQUENCE 437 AA; 50330 MW; 38747C2DAEB1CAFF CRC64;
MSKYIPGNQK HLTLDDRKYI EKSLNQGLSF KEVAKYLCKD PTTISKEIRV HRLSDWYHKG
TFYNAHNFCI HRYRCRKTNV CRKIILCDVK CSSCPTCNQT CPDFVRERCD RLDKAPYVCN
GCPKAINHCT IAHKCLYDAR FADRKYRELL SDSRSGISMT KHALRQKDMV ISPLISQGQS
PYQIVTNHPE LGMSVRTLYT YLDEGLFTAR NIDLKRKVKF KPRKSHNTQI RDRTVFQGRI
YAGFQALSPE HWTEMDTVHS SNESKKVLLT FFLKQEKLFL AFLMNRCTKG AVHMVFDRLE
KKLGAYDFLC LFGILLTDRG SEFGDPDALE TGIAGIERTN IYYCDPMRSG QKGGVENVHT
MLRMVLPKGT SFEFLTQWDV DLTVNHINST PRESLSGKTP YTAALEVYGE DVLKALQLRP
TAPDEVNLTP KLIKYNR
//
