ID R9JYI1_9FIRM Unreviewed; 311 AA.
AC R9JYI1;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Molybdenum cofactor synthesis domain-containing protein {ECO:0000313|EMBL:EOS39250.1};
GN ORFNames=C808_01665 {ECO:0000313|EMBL:EOS39250.1};
OS Lachnospiraceae bacterium M18-1.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235792 {ECO:0000313|EMBL:EOS39250.1, ECO:0000313|Proteomes:UP000014090};
RN [1] {ECO:0000313|EMBL:EOS39250.1, ECO:0000313|Proteomes:UP000014090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M18-1 {ECO:0000313|EMBL:EOS39250.1,
RC ECO:0000313|Proteomes:UP000014090};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium M18-1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the biosynthesis of molybdopterin.
CC {ECO:0000256|ARBA:ARBA00003487}.
CC -!- PATHWAY: Cofactor biosynthesis; molybdopterin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005046}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS39250.1}.
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DR EMBL; ASSV01000012; EOS39250.1; -; Genomic_DNA.
DR AlphaFoldDB; R9JYI1; -.
DR STRING; 1235792.C808_01665; -.
DR PATRIC; fig|1235792.3.peg.1799; -.
DR eggNOG; COG0521; Bacteria.
DR eggNOG; COG2258; Bacteria.
DR HOGENOM; CLU_077358_3_0_9; -.
DR OrthoDB; 9784492at2; -.
DR UniPathway; UPA00344; -.
DR Proteomes; UP000014090; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0006777; P:Mo-molybdopterin cofactor biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd00886; MogA_MoaB; 1.
DR Gene3D; 3.40.980.10; MoaB/Mog-like domain; 1.
DR Gene3D; 2.40.33.20; PK beta-barrel domain-like; 1.
DR InterPro; IPR036425; MoaB/Mog-like_dom_sf.
DR InterPro; IPR001453; MoaB/Mog_dom.
DR InterPro; IPR008284; MoCF_biosynth_CS.
DR InterPro; IPR005302; MoCF_Sase_C.
DR InterPro; IPR011037; Pyrv_Knase-like_insert_dom_sf.
DR NCBIfam; TIGR00177; molyb_syn; 1.
DR PANTHER; PTHR43764; MOLYBDENUM COFACTOR BIOSYNTHESIS; 1.
DR PANTHER; PTHR43764:SF1; MOLYBDOPTERIN MOLYBDOTRANSFERASE; 1.
DR Pfam; PF00994; MoCF_biosynth; 1.
DR Pfam; PF03473; MOSC; 1.
DR SMART; SM00852; MoCF_biosynth; 1.
DR SUPFAM; SSF53218; Molybdenum cofactor biosynthesis proteins; 1.
DR SUPFAM; SSF50800; PK beta-barrel domain-like; 1.
DR PROSITE; PS01078; MOCF_BIOSYNTHESIS_1; 1.
DR PROSITE; PS51340; MOSC; 1.
PE 4: Predicted;
KW Molybdenum cofactor biosynthesis {ECO:0000256|ARBA:ARBA00023150};
KW Reference proteome {ECO:0000313|Proteomes:UP000014090}.
FT DOMAIN 18..142
FT /note="MOSC"
FT /evidence="ECO:0000259|PROSITE:PS51340"
SQ SEQUENCE 311 AA; 33448 MW; 86A7FBEAB07E1802 CRC64;
MGIVKAVCIS ERRGIEKKNV NSAEFVEGFG IRGDAHGGNW HRQVSLLSAE RIEAFNKKGA
DVGHGAFGEN LVVDGFDFRA LPAGTTFQCN DVVLEMTQIG KECHTHCRIY QKMGECIMPT
QGVFAQVLHG GTISVGDEMR IIEKADTRYT AAVVTLSDKG AAGGREDTSG PCICEMLQEA
GYRVVERLLL PDEQARIEQE LTRLSDGRQV NLILTTGGTG FSERDRTPEA TMAVATRNAP
GIAEAIRMHS LSITGRAMLG RGASVIRNGT LIVNLPGSRK AVKESLEYIL PHLEHGIQIL
TGDGAECGGK G
//
