ID   R9KEZ0_9FIRM            Unreviewed;       841 AA.
AC   R9KEZ0;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Transglutaminase-like domain-containing protein {ECO:0000259|SMART:SM00460};
GN   ORFNames=C810_03092 {ECO:0000313|EMBL:EOS44848.1};
OS   Lachnospiraceae bacterium A2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS44848.1, ECO:0000313|Proteomes:UP000014150};
RN   [1] {ECO:0000313|EMBL:EOS44848.1, ECO:0000313|Proteomes:UP000014150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A2 {ECO:0000313|EMBL:EOS44848.1,
RC   ECO:0000313|Proteomes:UP000014150};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS44848.1}.
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DR   EMBL; ASSX01000017; EOS44848.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9KEZ0; -.
DR   STRING; 397290.C810_03092; -.
DR   PATRIC; fig|397290.3.peg.3428; -.
DR   eggNOG; COG1305; Bacteria.
DR   HOGENOM; CLU_339420_0_0_9; -.
DR   OrthoDB; 9804872at2; -.
DR   Proteomes; UP000014150; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014150};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        46..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        71..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        156..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        712..731
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          525..601
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          624..683
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        624..663
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   841 AA;  94318 MW;  2BD5048FFD3BA2D2 CRC64;
     MSGKTLPQTP KKEGILPKLQ RELSLFLLFF GTFLCLEKYL APGLPAAALA AAAGVCAVGA
     EVMRHGKAQK LAAFLLFGLL WGILAFQKQH LLADGAKEMA NRVLYLVNKY YRTDYLYWYV
     GQAGEGKQWL FLFLCFLLGF LGGFFLSLAK KNRSRNLAAL SIPLMAALAG LALGRVPSFA
     GIVLVLAGFF ALQLDFAARG MWALGACMGL SLGAAALAAQ GSFFQGLLET YHAPWLKRQL
     QLEDRMLEAV NQFSGIRLFS RNKAQKEFPL GNGKPRQEGK EILRITLDRR PGQAVYLRGF
     VGGDYGGGRW ESAPKQEFSD WAQKQGLSAD GCMEFVQNFP YRKFQAKGER GDGSVPQKVK
     IDLAEPSPGY TLVPYFTKIP EGQHMEGDGA LSPSRRKNFQ WDSFLHQEVF LHFGEYRQEY
     VEKEVAGERE LWEPYTDYAQ QVYTRLPKQG LERLQELADG YDYQWFTDEN AEETENQAAE
     EGRDFVFGER WSKVLRVMEL LWGNAEYSQE LKPLPEGEDF AEYFLLGQKK GYCVHFATAG
     TLVLRMYGIP ARYAAGYVVF PEDFKENRDG TFTASVTDLR GHAWTEIFEE GAGFVPLELT
     PPSYFPVLKE LKQGEDLEEA IRKQEHGEGW RESSAEGQEP EQEQEPLSQK ETETRREGQE
     RQEPQATAGE AQKEKGSGAK AGTGKAKILT DIQGRLSAAL KGAQEAFAKI PLAGKTAGTA
     LFASAAGYLL FYRRKRRKEE RQQAEFFQKD RAKGALAMGA AMKPMLKKLG LLQKPGLGEQ
     EYARFLEQEL PGMGWERTMS LLQKAAFSEH GISEEEFQEI AGAYRELGQR AREFQKRKIL
     P
//