ID   R9KQE3_9FIRM            Unreviewed;       353 AA.
AC   R9KQE3;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Integrase catalytic domain-containing protein {ECO:0000259|PROSITE:PS50994};
GN   ORFNames=C810_00443 {ECO:0000313|EMBL:EOS48563.1};
OS   Lachnospiraceae bacterium A2.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=397290 {ECO:0000313|EMBL:EOS48563.1, ECO:0000313|Proteomes:UP000014150};
RN   [1] {ECO:0000313|EMBL:EOS48563.1, ECO:0000313|Proteomes:UP000014150}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A2 {ECO:0000313|EMBL:EOS48563.1,
RC   ECO:0000313|Proteomes:UP000014150};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium A2.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS48563.1}.
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DR   EMBL; ASSX01000004; EOS48563.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9KQE3; -.
DR   PATRIC; fig|397290.3.peg.487; -.
DR   eggNOG; COG2826; Bacteria.
DR   HOGENOM; CLU_035706_0_2_9; -.
DR   OrthoDB; 9776104at2; -.
DR   Proteomes; UP000014150; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   CDD; cd00569; HTH_Hin_like; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR025246; IS30-like_HTH.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   NCBIfam; NF033563; transpos_IS30; 1.
DR   PANTHER; PTHR10948; TRANSPOSASE; 1.
DR   PANTHER; PTHR10948:SF23; TRANSPOSASE INSI FOR INSERTION SEQUENCE ELEMENT IS30A-RELATED; 1.
DR   Pfam; PF13936; HTH_38; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014150}.
FT   DOMAIN          175..349
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   353 AA;  40715 MW;  14A8A6C769F36CFD CRC64;
     MANKKGSHQL TRADRIKIEA LLKEGLSKAK IAKHLGVHRS TIYNELKRGE YEHRNSDWTT
     EIRYSPDIAQ EKAEENLKVR GTQLKIGNDI AYANYIEEKI VNEDYSPAAV LGELKAQGRE
     GEFNTTVCVA TLYSYIDKGV FLKLTNKDLP VKKNKKRGYK KVRKQQARAA AGDSIEKRPE
     EIDQREEFGH WEMDSVIGKR GVSKNVLLVL TERKTRDEII FKLPDHTDEA VVAALDRLER
     RYGADMFRQI FKTITVDNGS EFADVNGLER SILEEGEKRT HLYYCHPYSS WERGTNEVTN
     KMVRRKVPKG TNFDDKTDEE IEEIESWING YPRRIHGYRS AGELFTEELE KLA
//