ID R9L7K8_9FIRM Unreviewed; 2236 AA.
AC R9L7K8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Pectate lyase domain-containing protein {ECO:0000259|SMART:SM00656};
GN ORFNames=C809_01187 {ECO:0000313|EMBL:EOS51727.1};
OS Lachnospiraceae bacterium MD335.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235793 {ECO:0000313|EMBL:EOS51727.1, ECO:0000313|Proteomes:UP000014081};
RN [1] {ECO:0000313|EMBL:EOS51727.1, ECO:0000313|Proteomes:UP000014081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=COE1 {ECO:0000313|EMBL:EOS51727.1,
RC ECO:0000313|Proteomes:UP000014081};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium COE1.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361173}.
CC -!- SIMILARITY: Belongs to the polysaccharide lyase 1 family.
CC {ECO:0000256|RuleBase:RU361173}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS51727.1}.
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DR EMBL; ASSW01000016; EOS51727.1; -; Genomic_DNA.
DR STRING; 1235793.C809_01187; -.
DR PATRIC; fig|1235793.3.peg.1228; -.
DR eggNOG; COG3209; Bacteria.
DR eggNOG; COG3291; Bacteria.
DR eggNOG; COG3866; Bacteria.
DR eggNOG; COG5520; Bacteria.
DR HOGENOM; CLU_230809_0_0_9; -.
DR OrthoDB; 8660908at2; -.
DR Proteomes; UP000014081; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR006626; PbH1.
DR InterPro; IPR002022; Pec_lyase.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR PANTHER; PTHR16058; DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16058:SF4; DOUBLE ZINC RIBBON AND ANKYRIN REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13290; CHB_HEX_C_1; 4.
DR Pfam; PF13287; Fn3_assoc; 2.
DR Pfam; PF00544; Pectate_lyase_4; 1.
DR SMART; SM00656; Amb_all; 1.
DR SMART; SM00710; PbH1; 5.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361173};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU361173};
KW Polysaccharide degradation {ECO:0000256|RuleBase:RU361173};
KW Reference proteome {ECO:0000313|Proteomes:UP000014081};
KW Secreted {ECO:0000256|RuleBase:RU361173}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..31
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 32..2236
FT /note="Pectate lyase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039638208"
FT DOMAIN 792..996
FT /note="Pectate lyase"
FT /evidence="ECO:0000259|SMART:SM00656"
FT REGION 37..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1242..1267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2236 AA; 243369 MW; DE3DD1830CB25962 CRC64;
MTKKARKAIA RIMAVLMVFT LLPFQFSANM AMVEASETSE STGGGHKDDE AFSETDVEEA
ASAEDASADT ENVTVTQSES AEDTLTEDKT DMEQDEEGSV WVRDDDVTHE AEEAEEDKTE
KGYIEDNNLT DNTFSFTADD ISSELNISAG TPFPKGTQEY GKFTFLNKNG TPKITAANVT
YEGTTYINRF EFGSASSFVE NKESRLIRFE TGGRAIVTVC AYTGVEGRAI KIDRKEDGSA
DQEHVLQKNV IESHSFIVEA GQHDIWADSN YYILYVKVEE EAQKDKLAIP TAFPFNKEVK
VGDTITLSCD TEGASIFYTT DESDPKDNAS REEYTNGITI DFDMINADNN LIIKAYAAKE
GYDDSDTATF TYTVSTAPGE NQLERPTAEP DSAKVPRGTE VILKSADANA SIYYTLDETV
PNKDNGILFD EAAPIVINEA TTIKAIATAD GKDDSFPATF TYTIKQPKIV VEKDSASIIS
SVEPEGDISF INQDSKEVFD IQLKAETNAS PSNDIKTKAE ELKEDGGEIL YYDFTLINVE
ATTDTVSLAQ DIQGKLKIKM PYSLVSKMSK RNEIAVLHNT DVVEVTKEAD GFCFYADSFS
PYTVIVNPAP AVQGIAITES AGYEEGAYAE WEAVDGADGY MAYVAPAGGK YTRIDDELIR
KYDNYWRVDT VGLAKGIYYI KIDAVVLGED NGKATATVIA TNATKALKVT NYDRSGFAFS
DKSPLKTGSG AYNDDGTLKD GAQVIYVTKD TAKTCKAMIH INGESKPAEE VTGLQTILDA
KQKRGTSNDI LDIRIIGCVN LEDLDKISSS AEGIQIKGNA ARTPMNITLE GIGEDAVAKG
FGFLIRNCGN VEFRNFGILD FMDDGVSIDT DNCNLWIHDL DLFYGQAGGA ADQKKGDGTI
DIKLSQYCTV SYNHFWDSGK SCLIDASPKT DNYADYLTYH HNWFDHSDSR HPRIRNGHNF
HIYNNYYDGN SKYGVGSTTG SSAFVEANYF ENCNYPMMIS MQGTDALGTG TFSKENGGMI
KAYANHIEGE KSYLPYSSTN KTEFDAYEVN DASEQVPESV TAKAGASSYN NFDTSADMYF
YVADTAADAK ENVKKYAGRL NGGDLRWTFD ASENTNYAVI PALKEAVVNY KTSVKTIGGG
VEGNPAVIDG DDSMAGPGDD LTSVSAPMAN KPTNTQVEKG TKITLSCDTA GAQIYYTING
GVPTQGSIHY TDAIEIKGTT TIRAIAILGN AVSDVSIFKY TVPGEPGEGD NPGGDDNPGG
DDQPANTKIV TYEFNPQGAN MSADTIMPAE DTKYGTDNYF VIGNTNEKGK IAKANTNAPI
PSKSSVTGKY TVHYQFGGTA ATANDPRAIR FTTSNKARVS VAAFRTGTDE RNIYLDTDGN
VKVLSASVAE YMFDIIEAGT HGIYAKDGDI AVLYVIVEEF VPITEDPGDN TEVKAPYSTV
SQGEVLKGTK VELKCDTPNA VIYYTTDGTV PTTASTRYTQ PVVIDKDITI KAIASLNGVT
SQSVTFQYKV KQDDNKVRTP EPNYPSGEKL RKGTEITLTS DESAVIYYTL DGKEPTKQSI
LYTEPIVIET ATIIKAFAVK EGLSDSAVIT LEYTVFENAD VEQAAEPKAD IKSGTVKKGT
KITLTSDTPG AQIYYTLDDT VPTEDSTLYT EPIEINISTT IKAFAVKQDY MSSTIATFEY
NVIEDGLRIA FKNANETYTY TGSAIKPDIV VWNNSDKLVE GTDYTVKYTN NINASVDAKE
NKKPKITVTG KGNLTGTATT IFEIQKKQLE DTKRGADPVV IGGVTDNGEL IVVEKSKVTP
AVYYGGVKLT NKDYSVSKTD KCEITDEGKA ITITGKGNFA GTLTYDLKVI RKNELKKFTV
SFAAPNYTYN GEPQKIELKD SDVKDADGNI LKEGQNYTVV YQNDLTNAGT VKLTVVGLGY
YTGSVAKSYT IKPNAVTSGM EITGVSSEPY PYTGLGVTIP AIGVSYQGIP LEEGRDYKLA
YGSNKKVGTA KCTVSFMGNY KGSKAVSKNF TIGANSLTDE TEGVKIVIPN MVFNRPGVYK
SKPYVSVNGV EVKASEYTVK YYTDKDRTAE MGKIMEADTE VYVKIEGKDK SNYKGMLLTA
SYKVQKKPET AIDLSKAKVT VYTDWSDSAT KTNKFEYTGK EIEPSVMIEI KQGNVTLSPK
NVKQLMDEEK LTITYTNNIH KGKAAMIING DGETYVGSKT ATFSITTKNI KDTKILDDLF
EKIAAMCSVR YLVEAP
//
