ID R9LWZ8_9FIRM Unreviewed; 477 AA.
AC R9LWZ8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=C816_03905 {ECO:0000313|EMBL:EOS62846.1};
OS Oscillibacter sp. 1-3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Oscillibacter.
OX NCBI_TaxID=1235797 {ECO:0000313|EMBL:EOS62846.1, ECO:0000313|Proteomes:UP000014108};
RN [1] {ECO:0000313|EMBL:EOS62846.1, ECO:0000313|Proteomes:UP000014108}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1-3 {ECO:0000313|EMBL:EOS62846.1,
RC ECO:0000313|Proteomes:UP000014108};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Oscillibacter bacterium 1-3.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS62846.1}.
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DR EMBL; ASTC01000030; EOS62846.1; -; Genomic_DNA.
DR RefSeq; WP_016324147.1; NZ_KE159711.1.
DR AlphaFoldDB; R9LWZ8; -.
DR STRING; 1235797.C816_03905; -.
DR PATRIC; fig|1235797.3.peg.4310; -.
DR eggNOG; COG2205; Bacteria.
DR HOGENOM; CLU_000445_89_6_9; -.
DR Proteomes; UP000014108; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR45436:SF5; SENSOR HISTIDINE KINASE TRCS; 1.
DR PANTHER; PTHR45436; SENSOR HISTIDINE KINASE YKOH; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000014108};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 189..241
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 263..476
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 233..260
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 477 AA; 52495 MW; 00F4758BBE3E85AF CRC64;
MKFHLKMTLC MLAVLAALFG AGGSLLISES FEDSLEREKT AALGDYRMAW GILQIVNSMD
TYLDRDAIVK TMEQLYQQNS ASWSALRLST GDEVLYENRG TQSSLIQTAW SIEDPTPGIC
LFRILDNGAG AHFLVFSGAV ETNGDVLYLT TSHDVSALYT ARQAQQHTYL QVFFLMCVLC
AALSYTVSRL LTAPLGGLSR ASRAIAAGNF ASRVRVRSND EIGAVSTDFN TMAEKMEQTV
SELNRAVEEL HQAMERQEQF TGSFAHEMKT PMTSLIGYAE LLRSGTLTPE EQLEAADYLY
SEGKRLESLS HKLLELLVLK RHDLPFAKVS PAELIEALVE RLRPLYAAKG IRLSCVCKAG
ACLMDADLVW SLLLNLADNA QKAIEQGGEI QFRQEMLADG CLIHVLDSGR GIPPQALEHL
TEAFYRVDKA RSRAQGGFGL GLSLCREIAA LHNGRIRFEN RPEGGACVTV DLRGGRP
//
