ID R9MLM2_9FIRM Unreviewed; 467 AA.
AC R9MLM2;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=FtsK domain-containing protein {ECO:0000259|PROSITE:PS50901};
GN ORFNames=C818_00081 {ECO:0000313|EMBL:EOS71935.1};
OS Lachnospiraceae bacterium MD308.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1235799 {ECO:0000313|EMBL:EOS71935.1, ECO:0000313|Proteomes:UP000014117};
RN [1] {ECO:0000313|EMBL:EOS71935.1, ECO:0000313|Proteomes:UP000014117}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-2 {ECO:0000313|EMBL:EOS71935.1,
RC ECO:0000313|Proteomes:UP000014117};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Lachnospiraceae bacterium 3-2.";
RL Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOS71935.1}.
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DR EMBL; ASTE01000001; EOS71935.1; -; Genomic_DNA.
DR AlphaFoldDB; R9MLM2; -.
DR STRING; 1235799.C818_00081; -.
DR PATRIC; fig|1235799.3.peg.84; -.
DR eggNOG; COG1674; Bacteria.
DR HOGENOM; CLU_041426_3_0_9; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000014117; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR22683:SF47; FTSK DOMAIN-CONTAINING PROTEIN YDCQ; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50901; FTSK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Reference proteome {ECO:0000313|Proteomes:UP000014117};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..399
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 235..242
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 467 AA; 54090 MW; ECC391BDCC939F9E CRC64;
MQQFKKKGNR IRASDKSLVF RFATGSLLLL FFMAMILLNL KVIITTDWNS VTLFSDGNLQ
FHFTPYRLVT LIISAFTCLA AALLYYRFRY DKVKRLFHRQ KLARMILENG WYEVETSQDN
GIFKDLPSNG KKERITYFPK MYYRMENGLL YIQTEITLGK YQDQLLHLEK KLETGLYCEL
VSKELHDSYV EYVLLYDTIA NRITINEVRA EKGKLRLMKN IWWEYDKLPH MLIAGGTGGG
KTYFILTIIE TLLRCDSVMY VLDPKNADLA DLAAVMPEVY YKKEDITACI DRFYNGMMER
SETMKLMENY KTGENYAYLG LPPHFLIFDE YVAFMEMLTT KENAAVLNKL KQIVMLGRQA
GYFLILACQR PDAKYLGDGI RDQFNFRVAL GRMSELGYSM MFGEVNKDFF LKQIKGRGYV
DTGTSVISEF YTPLVPKGHD FLKEIGKLTQ NRQDGQAACK AKAASTD
//
