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Database: UniProt
Entry: R9MX99_9FIRM
LinkDB: R9MX99_9FIRM
Original site: R9MX99_9FIRM 
ID   R9MX99_9FIRM            Unreviewed;       236 AA.
AC   R9MX99;
DT   24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT   24-JUL-2013, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=Stage 0 sporulation protein A homolog {ECO:0000256|ARBA:ARBA00018672};
GN   ORFNames=C819_02408 {ECO:0000313|EMBL:EOS75418.1};
OS   Lachnospiraceae bacterium 10-1.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1235800 {ECO:0000313|EMBL:EOS75418.1, ECO:0000313|Proteomes:UP000014134};
RN   [1] {ECO:0000313|EMBL:EOS75418.1, ECO:0000313|Proteomes:UP000014134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=10-1 {ECO:0000313|EMBL:EOS75418.1,
RC   ECO:0000313|Proteomes:UP000014134};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A., Xavier R., Elson C., Duck W., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium 10-01.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play the central regulatory role in sporulation. It may
CC       be an element of the effector pathway responsible for the activation of
CC       sporulation genes in response to nutritional stress. Spo0A may act in
CC       concert with spo0H (a sigma factor) to control the expression of some
CC       genes that are critical to the sporulation process.
CC       {ECO:0000256|ARBA:ARBA00024867}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOS75418.1}.
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DR   EMBL; ASTF01000019; EOS75418.1; -; Genomic_DNA.
DR   AlphaFoldDB; R9MX99; -.
DR   STRING; 1235800.C819_02408; -.
DR   PATRIC; fig|1235800.3.peg.2571; -.
DR   eggNOG; COG3279; Bacteria.
DR   HOGENOM; CLU_000445_14_2_9; -.
DR   OrthoDB; 2063459at2; -.
DR   Proteomes; UP000014134; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 2.40.50.1020; LytTr DNA-binding domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR046947; LytR-like.
DR   InterPro; IPR007492; LytTR_DNA-bd_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR37299:SF1; STAGE 0 SPORULATION PROTEIN A HOMOLOG; 1.
DR   PANTHER; PTHR37299; TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR   Pfam; PF04397; LytTR; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00850; LytTR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   PROSITE; PS50930; HTH_LYTTR; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014134}.
FT   DOMAIN          2..121
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          142..231
FT                   /note="HTH LytTR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50930"
FT   MOD_RES         58
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   236 AA;  28048 MW;  B4FEF896CA2C9F53 CRC64;
     MLIAVCDDEK FYREKVQKLL ENYLSGYKIN YTIQLFSSGE EFLQENENKV KFDIVFMDIN
     MSRMDGIRTA LQMRSVHSHT YIVLITAFIQ YALEGYKVDA VRYIMKDTLD SALDECMDTI
     LKKMQLSRIN FSFLEGEKWL YTDNIFYVES QRHKAVFFYL DEKMENYHIY EKLDVIEERL
     SGYGFLRIHK SYLVNMKHIC RISNYTAYLD NGEELSVPRL KYQAVKEEFV AFKGAV
//
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