ID R9P5M8_PSEHS Unreviewed; 1920 AA.
AC R9P5M8;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Potential transmembrane protein {ECO:0000313|EMBL:GAC93390.1};
GN ORFNames=PHSY_000955 {ECO:0000313|EMBL:GAC93390.1};
OS Pseudozyma hubeiensis (strain SY62) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Pseudozyma.
OX NCBI_TaxID=1305764 {ECO:0000313|EMBL:GAC93390.1, ECO:0000313|Proteomes:UP000014071};
RN [1] {ECO:0000313|Proteomes:UP000014071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY62 {ECO:0000313|Proteomes:UP000014071};
RX PubMed=23814110; DOI=10.1128/genomea.00409-13;
RA Konishi M., Hatada Y., Horiuchi J.;
RT "Draft genome sequence of the basidiomycetous yeast-like fungus Pseudozyma
RT hubeiensis SY62, which produces an abundant amount of the biosurfactant
RT mannosylerythritol lipids.";
RL Genome Announc. 1:E0040913-E0040913(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; DF238776; GAC93390.1; -; Genomic_DNA.
DR RefSeq; XP_012186977.1; XM_012331587.1.
DR STRING; 1305764.R9P5M8; -.
DR GeneID; 24106256; -.
DR eggNOG; KOG1134; Eukaryota.
DR HOGENOM; CLU_002081_0_0_1; -.
DR OrthoDB; 1703463at2759; -.
DR Proteomes; UP000014071; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF146; EXPRESSED PROTEIN; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014071};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 720..740
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 768..788
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 800..821
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 865..883
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 889..907
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 927..948
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..224
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 393..659
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 673..944
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 250..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 447..509
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1117..1208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1224..1316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1501..1665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1693..1804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1843..1920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 447..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1254..1281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1505..1571
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1600..1627
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1748..1778
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1782..1797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1853..1888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1920 AA; 212499 MW; B11C25F469F4C7AE CRC64;
MADANERQIN SSFQGLVSTC VIFAVVGGIS ATTYESLRQL RRLPRTRFTK FWRKDAQRRH
PPGGVQDTPA HIRDGDTCED WEMGHFYLSR VFHATTPSPM LPRWPFAWVK RAIYFTDEWY
ADHTGMDTVV YVRFLRACLW WVLLQALTTA PILLSIHITF SRGVSTTDMQ RASLSYLVST
PAPDCKENDR AKCPTVPNEK GRSLLWIHLV LLWYLSITWV LALWWIGTGS LRVRKAQIAK
TRNKVIQAKA DARSAPANNT TTTANGVGPL HRDASANLTT AHGLSMDNSD GWRQRTLMVM
NLPATMRDEA SIRRYFEEFL RPDDADSLSD DGHSDDGAHP FSRNQDAQNA SGSDSDHRSA
SAEHRATPAV FSAHSDGPNG PEPDLHPDRH LKSPIQTVVL VRKMNELASM LSRRQEVLTQ
LEAAHVKLAQ EVLVTVGRRT LKMRKEERLK AQEGSHPSKE HRSQPRSFFK RVFRLRRQSK
QAQATNDSNS GNTTPSETLD PDIEKLGPSQ HTAGKALEEE LARRLARFSP TNRGTHTKQT
QTIQHNDSSN ENEIGETVWE ALNELPRELL DPFQPATRLS ALFRGQTVPT IDYLLTKLNL
LTALVTEMRS RPPTSYEPTS TAFVTFRDPR QARMVWRELK DQIVVKVRLA PEVKDLDWDR
LMKTSFTVDV VRGFGVSVVT WGFTIFWVII INAIVLGIFS VDKLKQIPGL GNFFDNNPKL
TGFVTITLPP LLVSLASMSV PELIFQVSKR AQGFVTFSAL YDMCLARYWK FVICNVVIFF
SVGSAVIVTV LTKVGNTGSI LSTVASAFPS AAPFFVSYLI LQLGLQSGFE HMGFMIALLQ
HMGARKAATP RIRAIKTLPR NFNRYYWLPL HINIMAIVFI FALLNPLVIP FALVYLALAL
VIFKKNFAYH YYRRFNEMEG VVYFVRLLRY SLDAIVVMQA VLLIFFSVLK KQPVYIGMSA
VLIPLTVITK IIATRLWRSQ CRALDDEEAE ALCGIDSRPL WQKMQRDDLG PSTAEEGSDS
RAPLDALASG RYPSVVPPPP TESAFQRVWQ RLHDSFNANG LDGQSYLATA HAKGKAPAGP
VGAGARGIAR TPRYIVKETA KHAFHFRHAA KNSLGMNVLV ESPRASRDRP STERRRPVSG
LPPTSQLHLH SFRNSQDEPA DVAAGAEHTD GEVPNDPAAA LRSGKSTIRK AKGDHVVHRR
RGSSRSEDRP FLSAFDAVSA HAPLPSEHDY DLSFEDGDAP FLEHDDQGHL LRQSSRQSRR
AASRNYGTLR RKTSQLATVA DEELPQSADS YASGGHAEDA TSSDPLYQRA SRPTEQATVN
VNQTWGRSIQ HSSYEDYDDS LKGRELVRPH PPVRWDDTPN NTARYNNPFY IQEMDEFLWL
PRNPLAPVDL FDTIEWYGPA LVSSQGGGGI VGEWDDEQDD GEFDTEDEEK HALHHDEIPF
GGEAATLARS KTLMLEGDEE ILLPDRLARH LEETQDAEQT VDPAASIPKN MMEDYKRALG
RTNRAGSRAS DSQASPTRSS LFRRGSNVSS PSAQNFAGGA SLLQIPSHGS FRSSDGIQPP
ASPTQMRMSP RPGTGDSVPL PSVAEGNVVV PHRSSSRRKR NKGPADEGDE EVLEGADADR
TTDLTPTKRR EINAMSANRN VSRRTYRRDA SGAMSRASGF SGGTTQRTVT LQAALRAEAL
EEERRLTLKQ RLAAAKGRKK REASRDVSGG HLDGLGETDA DGIDDGEDEE GGGTTTRRGA
SKSSIMARYE AQHRRREAHA SEFGEMSTPR KDGEMRRDIS QGSQLADMSQ GQLDRSASGA
SAFGRGRFRS AALGVLSLSR SPRVGGQDGT PVIISSMPMQ ELRGAHRPTT GGASIHGSPS
KPIATTNATE AQERQQPVQG SQAVQTCATE LALPAEASRS SALDKSVEVP LDPADGGPSK
//
