ID R9P7Y4_PSEHS Unreviewed; 1225 AA.
AC R9P7Y4;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Peregrin (Bromodomain and PHD finger-containing protein 1) {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHSY_001781 {ECO:0000313|EMBL:GAC94210.1};
OS Pseudozyma hubeiensis (strain SY62) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Pseudozyma.
OX NCBI_TaxID=1305764 {ECO:0000313|EMBL:GAC94210.1, ECO:0000313|Proteomes:UP000014071};
RN [1] {ECO:0000313|Proteomes:UP000014071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY62 {ECO:0000313|Proteomes:UP000014071};
RX PubMed=23814110; DOI=10.1128/genomea.00409-13;
RA Konishi M., Hatada Y., Horiuchi J.;
RT "Draft genome sequence of the basidiomycetous yeast-like fungus Pseudozyma
RT hubeiensis SY62, which produces an abundant amount of the biosurfactant
RT mannosylerythritol lipids.";
RL Genome Announc. 1:E0040913-E0040913(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DF238783; GAC94210.1; -; Genomic_DNA.
DR RefSeq; XP_012187797.1; XM_012332407.1.
DR AlphaFoldDB; R9P7Y4; -.
DR STRING; 1305764.R9P7Y4; -.
DR GeneID; 24107076; -.
DR eggNOG; KOG0955; Eukaryota.
DR HOGENOM; CLU_003589_0_0_1; -.
DR OrthoDB; 163389at2759; -.
DR Proteomes; UP000014071; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04369; Bromodomain; 1.
DR CDD; cd15492; PHD_BRPF_JADE_like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF164; BROMODOMAIN-CONTAINING PROTEIN, 140KD, ISOFORM A; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014071};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 155..205
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 209..336
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 557..627
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1129..1194
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 133..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 939..1118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 791..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 818..843
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..889
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 906..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 983..1035
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1225 AA; 135659 MW; E1DFABAFC91DFFEB CRC64;
MPGIPSKPNN IPLASSLPKV SFRKVPPDEA LIFHIPPGII DVHTLPFGFN DGSDYEKPHH
YIRYLEPIEG DLKRQVEYDM DEQDQEWLDA LNHDRRKDGL DTISYEVFEI ILDQLEKEWF
DLMKRVPPKA RHGAAADLTG DGADAQDADS DGGEDSKCAI CDDGECENSN AIVFCDGCNL
AVHQDCYGIP YIPEGQWLCR KCTVSPDRAV SCILCPHEGG AFKQTTTGKW AHLLCAMWIP
ETGVSNPVYM EPIDSVERIP KARWKLQCYL CRYKMGACIQ CDNRSCFTAF HVTCARKAGL
LFRTERTRVS HHLYDDSDNS DDEGSEVLRA CCHRHMPPNM RHQFKIDFGR QAAADDDRSE
TSYRTSPFVS SRTRELSVEF GVGAPLISVS RRSSLVGSHD SASATNDARS TSKSARAYKK
SFKAGPPLVP AYIANRVLEY ITKVHLRKKA TAVQIIARYW SLKREARRGA PLLKRLHLEP
WTASTQNKEQ TDAQKGKKLH FLRSIRGDLE RVRMLVEQVR KREKEKLRQA QEIRNSLVEP
VLFPFHADLR AAVAKLEAVD RYGFFAQPVS RIDVPDYYDI VKEPMDWTAI KDKIATKTYE
SVDEMRQDVL KIATNAMTYN KADTPYHKAA TKILKMIPDV FNELAAIKTS HLVHHQQTKA
QAEAAANHQA QELRSDEHPS LESTSADTAY ADIRQQLLAL GLEPPTSLIS LLRDYRLMED
AEQTDLRQQA YGTHPLPPTV HVKAEEDAQA DGQEGQVATQ RCVPIAPVTN LMEDFIRQLY
VPPPSITNTA TVSPTATTNS KHSTVKTSAA APAEKGPVST ARKRKPSETQ PKEPVERRTT
RRSIAVEAAA APSTADDTNK QQAAAEAAPA TPARSRRRST QSSAQTAPTD EARRPLAEAE
RAEPMKKSTS QTSSKTQDGM QVKEDVGAHD SFLLFNTGWV LPEGSKRHRN SAARPEMIGQ
RPRKISAPES PGPSAGTGAA DLSKLATPQQ RPRSRTVLSS DYRSTPASST AKGSTRKPNR
RASQDANTAA SSPLTTDDEG AMDVAAESPA KSSRLKRSRA REASAAEASV NDNVDDDTKT
PSSTRRSART RTASADLAAS PPASKRQRTA SKGSPTKAAV DFVANPPAAG TKVWAKVDTF
PHFPAVVIRD RSDLPGEMLR TEPEDGRMVA VRFFGKQTSY GWITPQKLAP LMVDEGEDEK
YLRLAAKKGK TKQVRDAYEE AKTRE
//
