ID R9PB35_PSEHS Unreviewed; 1366 AA.
AC R9PB35;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAC98618.1};
GN ORFNames=PHSY_006212 {ECO:0000313|EMBL:GAC98618.1};
OS Pseudozyma hubeiensis (strain SY62) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Pseudozyma.
OX NCBI_TaxID=1305764 {ECO:0000313|EMBL:GAC98618.1, ECO:0000313|Proteomes:UP000014071};
RN [1] {ECO:0000313|Proteomes:UP000014071}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SY62 {ECO:0000313|Proteomes:UP000014071};
RX PubMed=23814110; DOI=10.1128/genomea.00409-13;
RA Konishi M., Hatada Y., Horiuchi J.;
RT "Draft genome sequence of the basidiomycetous yeast-like fungus Pseudozyma
RT hubeiensis SY62, which produces an abundant amount of the biosurfactant
RT mannosylerythritol lipids.";
RL Genome Announc. 1:E0040913-E0040913(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; DF238821; GAC98618.1; -; Genomic_DNA.
DR RefSeq; XP_012192205.1; XM_012336815.1.
DR STRING; 1305764.R9PB35; -.
DR GeneID; 24111484; -.
DR eggNOG; KOG1729; Eukaryota.
DR eggNOG; KOG4424; Eukaryota.
DR HOGENOM; CLU_006045_0_0_1; -.
DR OrthoDB; 53554at2759; -.
DR Proteomes; UP000014071; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR PANTHER; PTHR12673:SF159; RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR JJ; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000014071};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 339..575
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 605..784
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 927..990
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 140..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 233..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 844..877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1011..1030
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1043..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1113..1190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1270..1290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1335..1366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 779..806
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 55..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..165
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..288
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 844..861
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1146..1190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1275..1290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1366 AA; 145540 MW; E3451BA372FF1895 CRC64;
MASVPRRDSS ISFPTLPASP TKPSTQAQLP TFSTSQCFDH DEHISMPPPR AITKPAQPNR
NSVASDDSSA ASSADYFGNS VATSRPVSAT TLASSRPSSV ASNASSSSHV QGQLTACADL
LSPGLASALG LLPHQPNHIA FPSSSRSAAA QAPSDPSSSA RPAQRRVRAQ SAHTGALATR
RPALPTASNV NHRISVASVS SFESLPEDEI VHGFLAPGVM QSKSRATSYD RIARSTTLGH
SQPKEDVARS RTPERSGSAT SFDSASITNS SDESSAADHP SDSASAVSSS AASSAHVAAT
SSASSTSTIT AGSSRPSYFL RRAATAPAPV ADMTLLMAHR KRSARELLDT ERSFVASLTL
INQEYYQPLM ASLGKGKAPA TASPTASAPI LSRKSINDIF SNFYDIMQLS KELLSQLEER
LQVAVWPVAA HASTMSQIRP EMRWDASVDC IGDILATLAP FLKMYSLYVK NFSSALQRIE
HEQKTNEPFA RFLKETDQKR AAKEKITSAT GSVRHAFGYG LGFQAHLLTI VQRIPRYKLL
VDDLLKSTPE THPDHVDLVR AGHMIEQVAS YINENVRQHE MVLTMLGLQK SLQGLTEPLV
APGRALIKRG TLMKTCRRNI QPREFFLFTD CLIYASPISG SMESASAAWT ALAQRGGMYG
ASAMEQIYSS TSMLSPSSGA ASPIESVLTP PSMAPPLGPR ARLTSIPEPY TPLTGAIFSL
AGHQLQFRDK FGLRDCTVVS VDGTSVDGLR HCFEIRTPDK SFAVYAESQA SREAWVNSIR
DARSDLMSAR RTLKAEEDSI EAKRERRRSL YKVDASKAAS RRLSTQSLGA YLAATNLIGQ
DKTVATAEQP AETSTSRSVS QEREAPQRRS RVDSLPNLLM RPPSFPSFAA NGTSLSLANL
LAANATTAAP PALRVLEDYN APVWVPDNRA DKCCNCQEVF GMWRRKHHCR LCGQVVCWTC
SQRSFLIPSY HDGEPDRPAR ACDRCYDSVF PPESPDDSEA TATAPTVVAT SVAPDSADMS
SVPSTGTDES VAQTLDAYRM GTSGTETDVE SSRLGSPLTP PVMCDSPDAG AEQPSVRASD
VNAQSSAMVK KDGEVLRPKS LRFDALPPSE LAVGAADSRS DAGLTAPPSP TEASLPPAQA
AALPATSQVE RRSSVSARSS PVRPSQPPVL PTRSKSLAGP LASSSARVMS NDSRLNRASA
LEAHHLFTSH YRNSQIQAAT SGSGTFRLVT PRLTTPESEL PPGASKRSGF SPSIMDAGYF
GGAAGAIQED AEDENASQIP GTSAGTSPLK TSEPFKPWML HAMSPTGGAP QLRPARKRPL
SAAARLSSFY GPLLASSSSN KDVTQGRASQ VNASPSKLEA NDTNKI
//
