ID R9PRB6_AGAAL Unreviewed; 411 AA.
AC R9PRB6;
DT 24-JUL-2013, integrated into UniProtKB/TrEMBL.
DT 24-JUL-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=O-acetylhomoserine sulfhydrylase {ECO:0000313|EMBL:GAD03942.1};
DE EC=2.5.1.49 {ECO:0000313|EMBL:GAD03942.1};
GN ORFNames=AALB_4022 {ECO:0000313|EMBL:GAD03942.1};
OS Agarivorans albus MKT 106.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Agarivorans.
OX NCBI_TaxID=1331007 {ECO:0000313|EMBL:GAD03942.1, ECO:0000313|Proteomes:UP000014461};
RN [1] {ECO:0000313|EMBL:GAD03942.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Yasuike M., Nakamura Y., Kai W., Fujiwara A., Fukui Y., Satomi M., Sano M.;
RT "Draft Genome Sequence of Agarivorans albus Strain MKT 106T, an Agarolytic
RT Marine Bacterium.";
RL Genome Announc. 1:e00367-13(2013).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAD03942.1}.
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DR EMBL; BARX01000038; GAD03942.1; -; Genomic_DNA.
DR RefSeq; WP_016403709.1; NZ_BARX01000038.1.
DR AlphaFoldDB; R9PRB6; -.
DR STRING; 1331007.AALB_4022; -.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000014461; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000014461};
KW Transferase {ECO:0000313|EMBL:GAD03942.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT MOD_RES 206
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 411 AA; 44176 MW; 5F952DDD5C2A25AE CRC64;
MSFKGFTTQL VHCDRLAGVE EGAVHAPIHN SVPYGYAATQ DLVDVFQGKQ VGHAYARQST
PTLDYLQRKI AMLDESVASL VFGTGMAAIG TVFLTLLKAG DHIVASRFLF GNTSSIFGTL
KGYGIEVTLV DATSSDAVEQ ACQANTKMVF IETIANPATQ IVDLAGIGKL CEQRGLVYVV
DNTLTSSYLF QPKSVGASLI ITSLSKYVGG HGNALGGSVS DTGLFNWSAY PNIFEGYRSG
DPKMWGINQI KKKGLRDFGG ALSSQAAHLL SVGAETMALR MERQCANALA LAKMLDEHPK
VAKVYYPGLA SHPQHQRASD LFKHYGALVS FDLVDGINST EFLDKTNIVI NATHLGDNRT
LALPVAQTIY FEMGLEARQA SGISETMIRC SIGIEDTEDL LNDFEQALAS S
//
