ID R9QBH0_HPV16 Unreviewed; 163 AA.
AC R9QBH0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Helicase {ECO:0000313|EMBL:AFJ19555.1};
DE Flags: Fragment;
GN Name=E1 {ECO:0000313|EMBL:AFJ19555.1};
OS Human papillomavirus type 16.
OC Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes;
OC Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae;
OC Alphapapillomavirus; Alphapapillomavirus 9.
OX NCBI_TaxID=333760 {ECO:0000313|EMBL:AFJ19555.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:AFJ19555.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PNL8 488 C1 {ECO:0000313|EMBL:AFJ19555.1};
RA Dimitris T., Panayotis M.;
RT "Nucleotide analysis of HPV16 E1 ORF.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:AFJ19555.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PNL8 488 C1 {ECO:0000313|EMBL:AFJ19555.1};
RX PubMed=23881083; DOI=10.1007/s00705-013-1790-8;
RA Tsakogiannis D., Darmis F., Gortsilas P., Ruether I.G., Kyriakopoulou Z.,
RA Dimitriou T.G., Amoutzias G., Markoulatos P.;
RT "Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.";
RL Arch. Virol. 159:51-63(2014).
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DR EMBL; JQ768490; AFJ19555.1; -; Genomic_DNA.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.1310.10; -; 1.
DR Gene3D; 1.10.10.510; Zinc finger, large T-antigen D1 domain; 1.
DR InterPro; IPR001177; PPV_DNA_helicase_E1_C.
DR InterPro; IPR046832; PPV_E1_DBD.
DR InterPro; IPR046935; PPV_E1_DBD_sf.
DR InterPro; IPR037102; Znf_lg_T-Ag_D1_dom_sf.
DR Pfam; PF00519; PPV_E1_C; 1.
DR Pfam; PF20450; PPV_E1_DBD; 1.
DR SUPFAM; SSF55464; Origin of replication-binding domain, RBD-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:AFJ19555.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:AFJ19555.1};
KW Hydrolase {ECO:0000313|EMBL:AFJ19555.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 2..135
FT /note="DNA helicase E1 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF20450"
FT DOMAIN 140..163
FT /note="DNA helicase E1 C-terminal Papillomavirus"
FT /evidence="ECO:0000259|Pfam:PF00519"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AFJ19555.1"
FT NON_TER 163
FT /evidence="ECO:0000313|EMBL:AFJ19555.1"
SQ SEQUENCE 163 AA; 18602 MW; 748C600D5138A25E CRC64;
LYGVSFSELV RPFKSNKSTC CDWCNAAFGL TPSIADSIKT LLQQYCLYLH IQSLASSWGM
VVLLLVRYKC GKNRETIEKL LSKLLCVSPM CMMIEPPKLR STATALYWYK TGISNISEVY
GDTPEWIQRQ TVLQHSFNDC TFELSQMVQW AYDNDIVDDS EIA
//
