ID R9U337_BOTFB Unreviewed; 537 AA.
AC R9U337;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=GIY-YIG endonuclease {ECO:0000313|EMBL:AGN49019.1};
GN OrderedLocusNames=BC1G_20016 {ECO:0000313|EMBL:AGN49019.1};
OS Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis
OS cinerea).
OG Mitochondrion {ECO:0000313|EMBL:AGN49019.1}.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Sclerotiniaceae; Botrytis.
OX NCBI_TaxID=332648 {ECO:0000313|EMBL:AGN49019.1, ECO:0000313|Proteomes:UP000001798};
RN [1] {ECO:0000313|Proteomes:UP000001798}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B05.10 {ECO:0000313|Proteomes:UP000001798};
RG The Broad Institute Genome Sequencing Platform;
RA van Kan J., Stassen J., Cuomo C., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The genome sequence of Botryotinia fuckeliana B05.10 mitochondrial
RT assembly.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: To endonucleases of group I introns of fungi and phage.
CC {ECO:0000256|ARBA:ARBA00010045}.
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DR EMBL; KC832409; AGN49019.1; -; Genomic_DNA.
DR AlphaFoldDB; R9U337; -.
DR Proteomes; UP000001798; Mitochondrion.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd10445; GIY-YIG_bI1_like; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR006350; Intron_endoG1.
DR InterPro; IPR010896; NUMOD1.
DR InterPro; IPR003611; NUMOD3.
DR NCBIfam; TIGR01453; grpIintron_endo; 1.
DR Pfam; PF01541; GIY-YIG; 1.
DR Pfam; PF07453; NUMOD1; 1.
DR Pfam; PF07460; NUMOD3; 1.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00496; IENR2; 3.
DR SUPFAM; SSF64496; DNA-binding domain of intron-encoded endonucleases; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:AGN49019.1};
KW Hydrolase {ECO:0000313|EMBL:AGN49019.1};
KW Mitochondrion {ECO:0000313|EMBL:AGN49019.1};
KW Nuclease {ECO:0000313|EMBL:AGN49019.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001798}.
FT DOMAIN 80..166
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|PROSITE:PS50164"
FT REGION 326..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 441..537
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 59543 MW; A234B1A2C2DADF28 CRC64;
MLPFRHKREL LFGLAFGLCK KRSFSSTIIS NSDKSLNNIV SGKSKSDGAE VSFTSISKLG
AKVYVNPVES RELIRKDNNG KVGVYCWFNN VNGKFYVGSG DPLYMRLSDY YQDWYYVARA
STYIVRALAK HGMVNFSLVI LEYTTSDSLI KCEQKWMDLL KPEYNLNPKA VNSKGYIHTP
ESIEMMRSLA LGRKHSDQVK NLMSESRGGV NNSFYGKKHT AEALSLLRDT ALNRTKLSKP
GVEVVVTDLE TKLTSTYESI RKAAKAINSD IKSLSLIPLI SRREIRGIRE KSQLEKGINT
PYRGRYIIAA RDRKIREFSV SNSFNTNPLS NSLSSSSSNS SSSQEASAHE NEGVSDNENR
EVSDNESGYS SDSNRSAVSE SRDDYALNHM PTQDVPEDVL PRFVSTMELV ARESEGDPDI
GQLHADRYQA LKTEMDSRIE AGIMPRPNVG QVNIYSENGG PETSSGGSAE NKVGTETSSG
GGTNNVGTSS LSSFYSSNKR KNDETEEYSG QPSKKFQQDS SDIRSDTEPY DFTGGDE
//
