ID R9WN98_9BETC Unreviewed; 272 AA.
AC R9WN98;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 28-JUN-2023, entry version 23.
DE RecName: Full=Replicase polyprotein 1ab {ECO:0000256|ARBA:ARBA00022087};
DE AltName: Full=ORF1ab polyprotein {ECO:0000256|ARBA:ARBA00029611};
DE Flags: Fragment;
OS Betacoronavirus BtCoV/KCR260/Car_per/CRC/2012.
OC Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
OC Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
OC Betacoronavirus.
OX NCBI_TaxID=1346295 {ECO:0000313|EMBL:AGO01150.1};
RN [1] {ECO:0000313|EMBL:AGO01150.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=BtCoV/KCR260/Car_per/CRC/2012 {ECO:0000313|EMBL:AGO01150.1};
RX PubMed=23761408; DOI=10.1099/vir.0.054841-0;
RA Corman V.M., Rasche A., Diallo T.D., Cottontail V.M., Stocker A.,
RA Souza B.F., Correa J.I., Carneiro A.J., Franke C.R., Nagy M., Metz M.,
RA Knornschild M., Kalko E.K., Ghanem S.J., Morales K.D., Salsamendi E.,
RA Spinola M., Herrler G., Voigt C.C., Tschapka M., Drosten C., Drexler J.F.;
RT "Highly diversified coronaviruses in neotropical bats.";
RL J. Gen. Virol. 94:1984-1994(2013).
CC -!- SIMILARITY: Belongs to the coronaviruses polyprotein 1ab family.
CC {ECO:0000256|ARBA:ARBA00008087}.
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DR EMBL; KC633197; AGO01150.1; -; Genomic_RNA.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR046441; RdRp_CoV.
DR InterPro; IPR001205; RNA-dir_pol_C.
DR Pfam; PF00680; RdRP_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS51948; COV_NSP12_RDRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:AGO01150.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..272
FT /note="Nsp12 RNA-dependent RNA polymerase"
FT /evidence="ECO:0000259|PROSITE:PS51948"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:AGO01150.1"
FT NON_TER 272
FT /evidence="ECO:0000313|EMBL:AGO01150.1"
SQ SEQUENCE 272 AA; 30504 MW; 9729F4E787E56471 CRC64;
FVFEVVDKFF ECYDGGCLPA AQVVVNNLDK SAGYPFNRFG KARLYYESMT LEDQDKLFAY
TKRNILPTIT QMNLKYAISA KSRARTVAGV SICSTMTNRQ YHQKLLKSIA ATRNVPVVIG
TTKFYGGWDT MLKNLYRDVE NPELMGWDYP KCDRAMPNML RIFASLILAR KHSGCCNGNE
RFYRLANECA QVLSEMVLCT GGFYVKPGGT SSGDATTAYA NSVFNIAQAV TANVGALMSA
NGHKIVNSYV KELQYKLYNN IYRSAQLDDQ FV
//
