ID RN141_RAT Reviewed; 230 AA.
AC Q6IV57;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 27-MAR-2024, entry version 107.
DE RecName: Full=RING finger protein 141;
GN Name=Rnf141;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Sprague-Dawley; TISSUE=Testis;
RA Ma Y., Zhang S., Qiu W., Liu Y., Dong J., Xu W., Zhang G.;
RT "Molecular cloning of rat Rnf141 gene.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in spermatogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250|UniProtKB:Q8WVD5}; Lipid-
CC anchor {ECO:0000250|UniProtKB:Q8WVD5}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY621087; AAT45392.1; -; mRNA.
DR RefSeq; NP_001001800.1; NM_001001800.1.
DR RefSeq; XP_006230112.1; XM_006230050.3.
DR AlphaFoldDB; Q6IV57; -.
DR BMRB; Q6IV57; -.
DR BioGRID; 259183; 1.
DR STRING; 10116.ENSRNOP00000024561; -.
DR iPTMnet; Q6IV57; -.
DR PhosphoSitePlus; Q6IV57; -.
DR PaxDb; 10116-ENSRNOP00000024561; -.
DR Ensembl; ENSRNOT00055045863; ENSRNOP00055037595; ENSRNOG00055026572.
DR Ensembl; ENSRNOT00060035951; ENSRNOP00060029582; ENSRNOG00060020728.
DR Ensembl; ENSRNOT00065052270; ENSRNOP00065042993; ENSRNOG00065030287.
DR GeneID; 308900; -.
DR KEGG; rno:308900; -.
DR UCSC; RGD:1303154; rat.
DR AGR; RGD:1303154; -.
DR CTD; 50862; -.
DR RGD; 1303154; rnf141.
DR eggNOG; KOG1039; Eukaryota.
DR HOGENOM; CLU_080007_0_0_1; -.
DR InParanoid; Q6IV57; -.
DR OrthoDB; 930529at2759; -.
DR PRO; PR:Q6IV57; -.
DR Proteomes; UP000002494; Chromosome 1.
DR Bgee; ENSRNOG00000017900; Expressed in liver and 18 other cell types or tissues.
DR Genevisible; Q6IV57; RN.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; ISO:RGD.
DR GO; GO:0051865; P:protein autoubiquitination; ISO:RGD.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; ISO:RGD.
DR CDD; cd16545; RING-HC_RNF141; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR043400; RING-HC_RNF141.
DR InterPro; IPR047126; RNF141-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12109:SF3; RING FINGER PROTEIN 141; 1.
DR PANTHER; PTHR12109; RING FINGER PROTEIN 141-RELATED; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 2: Evidence at transcript level;
KW Lipoprotein; Membrane; Metal-binding; Myristate; Reference proteome; Zinc;
KW Zinc-finger.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q8WVD5"
FT CHAIN 2..230
FT /note="RING finger protein 141"
FT /id="PRO_0000056104"
FT ZN_FING 155..192
FT /note="RING-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT LIPID 2
FT /note="N-myristoyl glycine"
FT /evidence="ECO:0000250|UniProtKB:Q8WVD5"
SQ SEQUENCE 230 AA; 25471 MW; 108C42BCE49F8424 CRC64;
MGQQISDQTQ LVINKLPEKV AKHVTLVRES GSLTYEEFLG RVAELNDVTA KIAAGQEKHL
LFEVQPGSDS SAFWKVVVRV VCTKINKSSG IVEASRIMNL YQFIQLYKDI TSQAAGVLAQ
SSTSEEPDGN PSSVTSCQAS LWMGRVKQLT DEEECCICMD GRADLILPCA HSFCQKCIDK
WSDRHRNCPI CRLQMTGANE SWVVSDAPTE DDMANYILNM ADEAGQPHRP
//
