ID RPD1_ARATH Reviewed; 409 AA.
AC Q689D6; Q8GWI6;
DT 24-JUL-2013, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 24-JAN-2024, entry version 98.
DE RecName: Full=Protein ROOT PRIMORDIUM DEFECTIVE 1;
GN Name=RPD1; OrderedLocusNames=At4g33495; ORFNames=F17M5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, DISRUPTION
RP PHENOTYPE, AND MUTAGENESIS OF ARG-152 AND GLU-308.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=16407439; DOI=10.1104/pp.105.074724;
RA Konishi M., Sugiyama M.;
RT "A novel plant-specific family gene, ROOT PRIMORDIUM DEFECTIVE 1, is
RT required for the maintenance of active cell proliferation.";
RL Plant Physiol. 140:591-602(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 20-409.
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP MUTANT RPD1.
RX PubMed=14522871; DOI=10.1242/dev.00794;
RA Konishi M., Sugiyama M.;
RT "Genetic analysis of adventitious root formation with a novel series of
RT temperature-sensitive mutants of Arabidopsis thaliana.";
RL Development 130:5637-5647(2003).
CC -!- FUNCTION: Involved in pre-arranging the maintenance of the active cell
CC proliferation during root primordium development. Does not seem to be
CC involved in cell cycle progression. {ECO:0000269|PubMed:16407439}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, hypocotyls, cotyledons and
CC shoot apex. {ECO:0000269|PubMed:16407439}.
CC -!- DISRUPTION PHENOTYPE: Embryo lethal when homozygous.
CC {ECO:0000269|PubMed:16407439}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC43408.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB189464; BAD42412.1; -; mRNA.
DR EMBL; AL035678; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE86235.1; -; Genomic_DNA.
DR EMBL; AK118818; BAC43408.1; ALT_INIT; mRNA.
DR RefSeq; NP_680759.1; NM_148393.3.
DR AlphaFoldDB; Q689D6; -.
DR SMR; Q689D6; -.
DR PaxDb; 3702-AT4G33495-1; -.
DR ProteomicsDB; 227956; -.
DR EnsemblPlants; AT4G33495.1; AT4G33495.1; AT4G33495.
DR GeneID; 829487; -.
DR Gramene; AT4G33495.1; AT4G33495.1; AT4G33495.
DR KEGG; ath:AT4G33495; -.
DR Araport; AT4G33495; -.
DR TAIR; AT4G33495; RPD1.
DR eggNOG; ENOG502QVHJ; Eukaryota.
DR HOGENOM; CLU_024287_0_1_1; -.
DR InParanoid; Q689D6; -.
DR OMA; CAIEKLR; -.
DR OrthoDB; 470333at2759; -.
DR PhylomeDB; Q689D6; -.
DR PRO; PR:Q689D6; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q689D6; baseline and differential.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0010102; P:lateral root morphogenesis; IMP:TAIR.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; IMP:TAIR.
DR InterPro; IPR021099; PORR_domain.
DR InterPro; IPR045040; PORR_fam.
DR PANTHER; PTHR31476:SF9; PROTEIN ROOT PRIMORDIUM DEFECTIVE 1; 1.
DR PANTHER; PTHR31476; PROTEIN WHAT'S THIS FACTOR 1 HOMOLOG, CHLOROPLASTIC; 1.
DR Pfam; PF11955; PORR; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..409
FT /note="Protein ROOT PRIMORDIUM DEFECTIVE 1"
FT /id="PRO_0000423019"
FT DOMAIN 47..386
FT /note="PORR"
FT /evidence="ECO:0000255"
FT MUTAGEN 152
FT /note="R->W: In rpd1-2; impaired in adventitious root
FT formation at the restrictive temperature of 28 degrees
FT Celsius."
FT /evidence="ECO:0000269|PubMed:16407439"
FT MUTAGEN 308
FT /note="E->K: In rpd1-1; impaired in adventitious root
FT formation and maintenance of callus cell proliferation at
FT the restrictive temperature of 28 degrees Celsius."
FT /evidence="ECO:0000269|PubMed:16407439"
FT CONFLICT 236
FT /note="D -> G (in Ref. 4; BAC43408)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 409 AA; 48286 MW; AB398ED62BD6E3FA CRC64;
MKLFLRNAFK TLNPKRKLAT TILPSINLIL VKPFSQSTTI PKKQDRVRDH GYDNYMEVEK
KIRKVVKFHS LILSQPNHTI AISLLDTLAR RLGLGFKQHE PGAFLLKFPH VFEIYEHPVQ
RILYCRLTRK ALDQIRHEHE AVLDQIPDAV TRLRKLVMMS NTGRIRLEHV RIARTEFGLP
EDFEYSVILK HPQFFRLIDG EETRDKYIEI VEKDPNLSIC AIERVREIEY RTKGIDAEDV
RFSFVVNFPP GFKIGKYFRI AVWKWQRLPY WSPYEDISGY DLRSMEAQNR LEKRSVACIH
ELLSLTVEKK ITLERIAHFR NVMNLPKKLK EFLLQHQGIF YISTRGNYGK LHTVFLREGY
KRGELVEPND VYLARRRLAE LVLMSPRKAK VDAELVRYRD GLDDEDDVE
//
