ID RS8_STRPN Reviewed; 132 AA.
AC P66632; Q97SU8;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE RecName: Full=Small ribosomal subunit protein uS8 {ECO:0000255|HAMAP-Rule:MF_01302};
DE AltName: Full=30S ribosomal protein S8 {ECO:0000305};
GN Name=rpsH {ECO:0000255|HAMAP-Rule:MF_01302}; OrderedLocusNames=SP_0224;
OS Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=170187;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-334 / TIGR4;
RX PubMed=11463916; DOI=10.1126/science.1061217;
RA Tettelin H., Nelson K.E., Paulsen I.T., Eisen J.A., Read T.D.,
RA Peterson S.N., Heidelberg J.F., DeBoy R.T., Haft D.H., Dodson R.J.,
RA Durkin A.S., Gwinn M.L., Kolonay J.F., Nelson W.C., Peterson J.D.,
RA Umayam L.A., White O., Salzberg S.L., Lewis M.R., Radune D.,
RA Holtzapple E.K., Khouri H.M., Wolf A.M., Utterback T.R., Hansen C.L.,
RA McDonald L.A., Feldblyum T.V., Angiuoli S.V., Dickinson T., Hickey E.K.,
RA Holt I.E., Loftus B.J., Yang F., Smith H.O., Venter J.C., Dougherty B.A.,
RA Morrison D.A., Hollingshead S.K., Fraser C.M.;
RT "Complete genome sequence of a virulent isolate of Streptococcus
RT pneumoniae.";
RL Science 293:498-506(2001).
CC -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC to 16S rRNA central domain where it helps coordinate assembly of the
CC platform of the 30S subunit. {ECO:0000255|HAMAP-Rule:MF_01302}.
CC -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts proteins S5 and
CC S12. {ECO:0000255|HAMAP-Rule:MF_01302}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uS8 family.
CC {ECO:0000255|HAMAP-Rule:MF_01302}.
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DR EMBL; AE005672; AAK74404.1; -; Genomic_DNA.
DR PIR; C95026; C95026.
DR RefSeq; WP_000245505.1; NZ_CP089948.1.
DR AlphaFoldDB; P66632; -.
DR SMR; P66632; -.
DR PaxDb; 170187-SP_0224; -.
DR EnsemblBacteria; AAK74404; AAK74404; SP_0224.
DR GeneID; 66805430; -.
DR KEGG; spn:SP_0224; -.
DR eggNOG; COG0096; Bacteria.
DR PhylomeDB; P66632; -.
DR BioCyc; SPNE170187:G1FZB-228-MONOMER; -.
DR Proteomes; UP000000585; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.30.1370.30; -; 1.
DR Gene3D; 3.30.1490.10; -; 1.
DR HAMAP; MF_01302_B; Ribosomal_uS8_B; 1.
DR InterPro; IPR000630; Ribosomal_uS8.
DR InterPro; IPR047863; Ribosomal_uS8_CS.
DR InterPro; IPR035987; Ribosomal_uS8_sf.
DR PANTHER; PTHR11758:SF4; 37S RIBOSOMAL PROTEIN S8, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11758; 40S RIBOSOMAL PROTEIN S15A; 1.
DR Pfam; PF00410; Ribosomal_S8; 1.
DR SUPFAM; SSF56047; Ribosomal protein S8; 1.
DR PROSITE; PS00053; RIBOSOMAL_S8; 1.
PE 3: Inferred from homology;
KW Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW rRNA-binding.
FT CHAIN 1..132
FT /note="Small ribosomal subunit protein uS8"
FT /id="PRO_0000126496"
SQ SEQUENCE 132 AA; 14754 MW; 3BBA430C1A1B576A CRC64;
MVMTDPIADF LTRIRNANQA KHEVLEVPAS NIKKGIAEIL KREGFVKNVE IIEDDKQGVI
RVFLKYGPNG EKVITNLKRV SKPGLRVYKK REDLPKVLNG LGIAILSTSE GLLTDKEARQ
KNVGGEVIAY VW
//
