ID   S0AYB2_ENTHI            Unreviewed;       514 AA.
AC   S0AYB2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Polyadenylate-binding protein, putative {ECO:0000313|EMBL:BAN39889.1};
OS   Entamoeba histolytica.
OC   Eukaryota; Amoebozoa; Evosea; Archamoebae; Mastigamoebida; Entamoebidae;
OC   Entamoeba.
OX   NCBI_TaxID=5759 {ECO:0000313|EMBL:BAN39889.1};
RN   [1] {ECO:0000313|EMBL:BAN39889.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HM-1:IMSS {ECO:0000313|EMBL:BAN39889.1};
RA   Hiranuka K., Kumagai M., Wakaguri H., Suzuki Y., Sugano S., Watanabe J.,
RA   Makioka A.;
RT   "Short 5' UTR of Entamoeba genes.";
RL   Submitted (JUN-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK421330; BAN39889.1; -; mRNA.
DR   EMBL; AK421594; BAN40129.1; -; mRNA.
DR   AlphaFoldDB; S0AYB2; -.
DR   VEuPathDB; AmoebaDB:EHI5A_191840; -.
DR   VEuPathDB; AmoebaDB:EHI7A_146030; -.
DR   VEuPathDB; AmoebaDB:EHI8A_170120; -.
DR   VEuPathDB; AmoebaDB:EHI_033250; -.
DR   VEuPathDB; AmoebaDB:KM1_242460; -.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd00590; RRM_SF; 2.
DR   Gene3D; 3.30.70.330; -; 4.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR036053; PABP-dom.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR24012:SF915; POLYADENYLATE-BINDING PROTEIN; 1.
DR   PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR   Pfam; PF00076; RRM_1; 3.
DR   SMART; SM00360; RRM; 4.
DR   SUPFAM; SSF63570; PABC (PABP) domain; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR   PROSITE; PS50102; RRM; 3.
PE   2: Evidence at transcript level;
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT   DOMAIN          15..93
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          103..194
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          189..272
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   REGION          404..438
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        409..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  58754 MW;  F6FD28A667D29256 CRC64;
     MTTAQSNFSD FAENKTIFVS GLSLNVTESV LYGTVLKEFP NQVLNVHINK DNSHDTSIAY
     INMNTHDSAA QAISKLNGTI IEGRKVNMFW SLRDYKLRTQ SETNLYVKGI KKEIGQQKMQ
     EVFDKYGNTL SVKLSTNEKN ESNGFGYVKY CTVDECKKVI AAKEEISKEI GEASFDIVKF
     EKQNKSLKTN IYIGNIDATV TEEQFLKYFE TFGPIRKDAS GKLAYKIVLD QAHQKNKGFV
     NYENVEDAQK AISSPKTGVL GSGEILIDYY KSKEERKKEW RNALFEIKNN VAGRYKDFNL
     YINTGKNHTT SDAEIREKLG SCGEIYSLQV KYYNKQPTEV AYCCFKDAQG AQNALAKASE
     LGWTINKFMT KQEKFISQNM YAQTAYPINF LNFFQMFNPN VIVPQHPQNQ NKEKDHRKKS
     TREESRKPKP IAEKQPKVEK APIINEDMKN ELGDQLYDYI LSLGLYDEDL TGRITGVLLE
     SIEYADLKKK IDTKSPELTV IIKEIVENLK KIQN
//