ID S0KLP3_9ENTE Unreviewed; 575 AA.
AC S0KLP3;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=HAMP domain-containing protein {ECO:0000259|PROSITE:PS50885};
GN ORFNames=OMK_01993 {ECO:0000313|EMBL:EOT40141.1};
OS Enterococcus dispar ATCC 51266.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1139219 {ECO:0000313|EMBL:EOT40141.1, ECO:0000313|Proteomes:UP000014127};
RN [1] {ECO:0000313|EMBL:EOT40141.1, ECO:0000313|Proteomes:UP000014127}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51266 {ECO:0000313|EMBL:EOT40141.1,
RC ECO:0000313|Proteomes:UP000014127};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus dispar ATCC_51266 (Illumina only
RT assembly).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT40141.1}.
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DR EMBL; AHYR01000009; EOT40141.1; -; Genomic_DNA.
DR RefSeq; WP_016173132.1; NZ_KE136354.1.
DR AlphaFoldDB; S0KLP3; -.
DR STRING; 44009.RV01_GL001406; -.
DR PATRIC; fig|1139219.3.peg.1932; -.
DR eggNOG; COG2972; Bacteria.
DR HOGENOM; CLU_020473_6_3_9; -.
DR OrthoDB; 9776552at2; -.
DR Proteomes; UP000014127; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000014127};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 304..357
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 575 AA; 65741 MW; 961F5BE90F8B708C CRC64;
MAKFLARFDK GKYLMNRLMQ IYSLLLVGVI LLTVAALCVY TADSNYRKMN SDLAGLENRV
MNSVEDNNDT MSFIYMELAG SNAAIDNVRQ YLNLSAADYF EYTQDSWLAY QRDTRISETI
NGFFNAFNDL EQLYVTLDGS SSYLMADKNN HNGRKLQGKI PPKSGFVITR PIVDQYGSKM
VGEVSAVFSR AAVLGMLENS MVSDGMDAYI FDNANNPMFT THNQLSPKGY QKLVSAVENK
QPIPKKISRK YYVLQRKTSR DLSYVLLASK KVLWQKNLRT FAIAILVGSG LAAVLLITLK
RTFRRYFQQI ETIVGITHSV AEGNLQERID VSKVQDELYD LSEAINFMIA SLDQYIRDNY
ELEIKQRDAH MQALQSQINP HFLYNTLEYI RMYALSKQQK ELADVVYAFS ALLRNNTTQE
KTTTLKKELS FCEKYVYLYQ MRYPDRVAYN FTIEPALEEL VIPKFTIQPL IENYFVHGID
YTRNDNAISV KAHFVDDDIV IYVIDNGKGM TPERLQEVQN KLKQIENEAQ NSIGMHNVYA
RLQNTFGIAF SMAIDSKLGK GTTLTIKIKG GHHFV
//
