ID S0KX55_9ENTE Unreviewed; 432 AA.
AC S0KX55;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Serine protease {ECO:0000256|RuleBase:RU004296};
DE EC=3.4.21.- {ECO:0000256|RuleBase:RU004296};
GN ORFNames=I573_00292 {ECO:0000313|EMBL:EOT87236.1};
OS Enterococcus sulfureus ATCC 49903.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=1140003 {ECO:0000313|EMBL:EOT87236.1, ECO:0000313|Proteomes:UP000015961};
RN [1] {ECO:0000313|EMBL:EOT87236.1, ECO:0000313|Proteomes:UP000015961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49903 {ECO:0000313|EMBL:EOT87236.1,
RC ECO:0000313|Proteomes:UP000015961};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A., Russ C., Gilmore M., Surin D., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Enterococcus sulfureus ATCC_49903 (PacBio/Illumina
RT hybrid assembly).";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the peptidase S1B family.
CC {ECO:0000256|ARBA:ARBA00008764, ECO:0000256|RuleBase:RU004296}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOT87236.1}.
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DR EMBL; ASWO01000001; EOT87236.1; -; Genomic_DNA.
DR RefSeq; WP_016184788.1; NZ_KE136393.1.
DR AlphaFoldDB; S0KX55; -.
DR STRING; 1140003.OMY_00297; -.
DR PATRIC; fig|1140003.3.peg.291; -.
DR eggNOG; COG3591; Bacteria.
DR eggNOG; COG3757; Bacteria.
DR OrthoDB; 191045at2; -.
DR Proteomes; UP000015961; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR043708; DUF5648.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR008256; Peptidase_S1B.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR000126; V8_ser_AS.
DR PANTHER; PTHR15462; SERINE PROTEASE; 1.
DR PANTHER; PTHR15462:SF8; SERINE PROTEASE; 1.
DR Pfam; PF18885; DUF5648; 3.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00839; V8PROTEASE.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS00673; V8_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004296};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004296};
KW Reference proteome {ECO:0000313|Proteomes:UP000015961};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU004296}; Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 105..294
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|Pfam:PF00089"
FT ACT_SITE 141
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR608256-1"
FT ACT_SITE 191
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR608256-1"
FT ACT_SITE 259
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR608256-1"
SQ SEQUENCE 432 AA; 47643 MW; E8FE93C3A8006A42 CRC64;
MSRYSQVKWL GLFSFLFILF TVSTVVADDQ MMITTSQHET YYLPESAATS LPPQIGTLIT
DDTMTLTPPT GLDGSLLYPL QENASSIAES ILATDERTHI TNTATYPYSA TVFITATFSN
GATYIGSGAM VSSDGVLTAG HMIYSAANGG WATNVTIYPG LNGTTAPFGS AKSIKLFSVT
EWTNKQDPTQ DIGLIRLDRP IGYKTGWFGL STSATPNETV QTTGFPAEKG ETMWKSTGKI
DTIENSRIYY DLDTTSGQSG SPVYNANRTL LATHTYGGSQ VNFGTRINST VLAWIESDTH
HYVANFRLYN RNSGEHFFTT NATEYQALVN LGWRAEGVAW FAAATGDEVY RLYNPNSGKH
FYTKSVTEKQ YLVRLGWHDE GVAYHVVANG IPVYRLYNKN DGRHFYTSSL YERNSLVQLG
WRAEGVAWYG LG
//
