ID   S1NHI6_ECOLX            Unreviewed;       723 AA.
AC   S1NHI6;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Protein traD {ECO:0000313|EMBL:EOW88480.1};
GN   ORFNames=A13A_05339 {ECO:0000313|EMBL:EOW88480.1};
OS   Escherichia coli KTE182.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=1181728 {ECO:0000313|EMBL:EOW88480.1, ECO:0000313|Proteomes:UP000014179};
RN   [1] {ECO:0000313|EMBL:EOW88480.1, ECO:0000313|Proteomes:UP000014179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KTE182 {ECO:0000313|EMBL:EOW88480.1,
RC   ECO:0000313|Proteomes:UP000014179};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Nielsen K.L., Frimodt-Moller N., Andersen P.S., Walker B.,
RA   Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Larimer J., McCowan C., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Escherichia coli KTE182.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOW88480.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ASUG01000071; EOW88480.1; -; Genomic_DNA.
DR   RefSeq; WP_016237229.1; NZ_KE136852.1.
DR   AlphaFoldDB; S1NHI6; -.
DR   PATRIC; fig|1181728.3.peg.5525; -.
DR   HOGENOM; CLU_016763_2_0_6; -.
DR   Proteomes; UP000014179; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR   Gene3D; 1.10.8.80; Magnesium chelatase subunit I, C-Terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014128; T4SS_TraD.
DR   InterPro; IPR019476; T4SS_TraD_DNA-bd.
DR   InterPro; IPR022585; TraD_N.
DR   NCBIfam; TIGR02759; TraD_Ftype; 1.
DR   PANTHER; PTHR37937; CONJUGATIVE TRANSFER: DNA TRANSPORT; 1.
DR   PANTHER; PTHR37937:SF1; CONJUGATIVE TRANSFER: DNA TRANSPORT; 1.
DR   Pfam; PF12615; TraD_N; 1.
DR   Pfam; PF10412; TrwB_AAD_bind; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        108..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          32..128
FT                   /note="TraD coupling protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12615"
FT   DOMAIN          172..561
FT                   /note="Type IV secretion system coupling protein TraD DNA-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF10412"
FT   REGION          607..635
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          656..675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        613..635
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   723 AA;  82090 MW;  CAE60A6A77BB662E CRC64;
     MSFNAKDMTQ GGQIASMRIR MFSQIANIML YCLFIFFWIL IGLILWVKIS WQTFINGCIY
     WWCTSLEGMR DLIKSQPVYE IQYYGKTFRM NAAQVLHDKY MIWCGEQLWS AFVLASVVAL
     VICLITFFVV SWILGHQGKQ QSENEVTGGR QLTDNPKEVA RMLKKDGKDS DIRIGDLPII
     RDSEIQNFCL HGTVGAGKSE VIRRLANYAR QRGDMVVIYD RSGEFVKSYY DPSIDKILNP
     LDARCAAWDL WKECLTQPDF DNTANTLIPM GTKEDPFWQG SGRTIFAEAA YLMRNDPNRS
     YSKLVDTLLS IKIEKLRTFL RNSPAANLVE EKIEKTAISI RAVLTNYVKA IRYLQGIEHN
     GEPFTIRDWM RGVREDQKNG WLFISSNADT HASLKPVISM WLSIAIRGLL AMGENRNRRV
     WFFCDELPTL HKLPDLVEIL PEARKFGGCY VFGIQSYAQL EDIYGEKAAA TLFDVMNTRA
     FFRSPSHKIA EFAAGEIGEK EHLKASEQYS YGADPVRDGV STGKDMERQT LVSYSDIQSL
     PDLTCYVTLP GPYPAVKLSL KYQARPKVAP EFIPRDINPE MENRLSAVLA AREAEGRQMA
     SLFEPEVASG EGVTQAEQPQ QPQQPQQPQQ PVSSVINDKK SDAGVSVPAG GIEQELKMKP
     EEEMEQQLPP GISESGEVVD MAAYEAWQQE NHPDIQQQMQ RREEVNINVH RERGEDVEPG
     DDF
//