ID S1PT37_ECOLX Unreviewed; 414 AA.
AC S1PT37;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Esterase FrsA {ECO:0000256|HAMAP-Rule:MF_01063};
DE EC=3.1.1.1 {ECO:0000256|HAMAP-Rule:MF_01063};
GN Name=frsA {ECO:0000256|HAMAP-Rule:MF_01063};
GN ORFNames=A13A_00270 {ECO:0000313|EMBL:EOX01434.1};
OS Escherichia coli KTE182.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=1181728 {ECO:0000313|EMBL:EOX01434.1, ECO:0000313|Proteomes:UP000014179};
RN [1] {ECO:0000313|EMBL:EOX01434.1, ECO:0000313|Proteomes:UP000014179}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KTE182 {ECO:0000313|EMBL:EOX01434.1,
RC ECO:0000313|Proteomes:UP000014179};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Feldgarden M., Nielsen K.L., Frimodt-Moller N., Andersen P.S., Walker B.,
RA Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Larimer J., McCowan C., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Escherichia coli KTE182.";
RL Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the hydrolysis of esters. {ECO:0000256|HAMAP-
CC Rule:MF_01063}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+);
CC Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01063};
CC -!- SIMILARITY: Belongs to the FrsA family. {ECO:0000256|HAMAP-
CC Rule:MF_01063}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EOX01434.1}.
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DR EMBL; ASUG01000017; EOX01434.1; -; Genomic_DNA.
DR RefSeq; WP_000189578.1; NZ_KE136858.1.
DR AlphaFoldDB; S1PT37; -.
DR SMR; S1PT37; -.
DR PATRIC; fig|1181728.3.peg.263; -.
DR HOGENOM; CLU_036819_0_0_6; -.
DR Proteomes; UP000014179; Unassembled WGS sequence.
DR GO; GO:0106435; F:carboxylesterase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR HAMAP; MF_01063; FrsA; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR043423; FrsA.
DR InterPro; IPR010520; FrsA-like.
DR PANTHER; PTHR22946:SF4; DLH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22946; UNCHARACTERIZED; 1.
DR Pfam; PF06500; FrsA-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01063};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487, ECO:0000256|HAMAP-
KW Rule:MF_01063}.
SQ SEQUENCE 414 AA; 47024 MW; DC63C8D46B0453E3 CRC64;
MTQANLSETL FKPRFKHPET STLVRRFSHG AQPPVQSALD GKTIPHWYRM INRLMWIWRG
IDPREILDVQ ARIVMSDAER TDDDLYDTVI GYRGGNWIYE WATQAMVWQQ KACAEEDPQL
SGRHWLHAAT LYNIAAYPHL KGDDLAEQAQ ALSNRAYEEA AQRLPGTMRQ MEFTVPGGAP
ITGFLHMPKG DGPFPTVLMC GGLDAMQTDY YSLYERYFAP RGIAMLTIDM PSVGFSSKWK
LTQDSSLLHQ HVLKALPNVP WVDHTRVAAF GFRFGANVAV RLAYLESPRL KVVACLGPVV
HTLLSDFKCQ QQVPEMYLDV LASRLGMHDA SDEALRVELN RYSLKVQGLL GRRCPTPMLS
GYWKNDPFSP EEDSRLITSS SADGKLLEIP FNPVYRNFDK GLQEITDWIE KRLC
//
