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Database: UniProt
Entry: S1PZP7_ECOLX
LinkDB: S1PZP7_ECOLX
Original site: S1PZP7_ECOLX 
ID   S1PZP7_ECOLX            Unreviewed;       471 AA.
AC   S1PZP7;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|ARBA:ARBA00016246, ECO:0000256|RuleBase:RU362066};
DE            Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE   AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN   ORFNames=A13A_01960 {ECO:0000313|EMBL:EOW97626.1};
OS   Escherichia coli KTE182.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=1181728 {ECO:0000313|EMBL:EOW97626.1, ECO:0000313|Proteomes:UP000014179};
RN   [1] {ECO:0000313|EMBL:EOW97626.1, ECO:0000313|Proteomes:UP000014179}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KTE182 {ECO:0000313|EMBL:EOW97626.1,
RC   ECO:0000313|Proteomes:UP000014179};
RG   The Broad Institute Genome Sequencing Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Feldgarden M., Nielsen K.L., Frimodt-Moller N., Andersen P.S., Walker B.,
RA   Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A.,
RA   Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Larimer J., McCowan C., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Escherichia coli KTE182.";
RL   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end. {ECO:0000256|RuleBase:RU362066}.
CC   -!- FUNCTION: Required for the morphogenesis and for the elongation of the
CC       flagellar filament by facilitating polymerization of the flagellin
CC       monomers at the tip of growing filament. Forms a capping structure,
CC       which prevents flagellin subunits (transported through the central
CC       channel of the flagellum) from leaking out without polymerization at
CC       the distal end. {ECO:0000256|ARBA:ARBA00025175}.
CC   -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC       ECO:0000256|RuleBase:RU362066}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC       Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC   -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC       ECO:0000256|RuleBase:RU362066}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EOW97626.1}.
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DR   EMBL; ASUG01000035; EOW97626.1; -; Genomic_DNA.
DR   RefSeq; WP_000146828.1; NZ_KE136862.1.
DR   AlphaFoldDB; S1PZP7; -.
DR   PATRIC; fig|1181728.3.peg.2017; -.
DR   HOGENOM; CLU_015182_8_1_6; -.
DR   Proteomes; UP000014179; Unassembled WGS sequence.
DR   GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR   GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR010810; Flagellin_hook_IN_motif.
DR   InterPro; IPR040026; FliD.
DR   InterPro; IPR010809; FliD_C.
DR   InterPro; IPR003481; FliD_N.
DR   PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR   PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR   Pfam; PF07196; Flagellin_IN; 1.
DR   Pfam; PF07195; FliD_C; 1.
DR   Pfam; PF02465; FliD_N; 1.
PE   3: Inferred from homology;
KW   Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW   ECO:0000256|RuleBase:RU362066};
KW   Cell projection {ECO:0000313|EMBL:EOW97626.1};
KW   Cilium {ECO:0000313|EMBL:EOW97626.1};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|RuleBase:RU362066};
KW   Flagellum {ECO:0000313|EMBL:EOW97626.1};
KW   Secreted {ECO:0000256|RuleBase:RU362066}.
FT   DOMAIN          11..106
FT                   /note="Flagellar hook-associated protein 2 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02465"
FT   DOMAIN          224..454
FT                   /note="Flagellar hook-associated protein 2 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF07195"
FT   COILED          410..437
FT                   /evidence="ECO:0000256|RuleBase:RU362066"
SQ   SEQUENCE   471 AA;  48830 MW;  2890B8AD334C6E64 CRC64;
     MASISTLGVG SGLDLSSILD SLEAAEKSTL TPISKQQSSY TAKLSAYGTL KSALESFQTA
     NTALNKADLF TATSTTSSSS AFSATTTGSA IAGKYTISVS QLAQAQTLTT KNSQKDSKAA
     IATSDSVLTI QQGGGKDPVT IDISAGNSSL SGIRDAINNA KAGVSASIIN VGNGEYRLSI
     TANDTGSDNA MKLSVSGDSA LESFMGYNGT PGDSSNGMIE SVTAQNAKLT VNNVEIENSS
     NTISDSLEDI TLNLNDVTTG NQTLTISKDT SKAENAVKAW VDAYNTLQDT FSSLTKYTAV
     DAGAESQDSS NGALLGDSTL RTIQTQLKTL LANTHSSSNY KTLAQIGITS DASTGKLEIA
     TDKLQTALKN DAAGIGEMFI GDGKSTGVTT GISSNLTSWL SSTGIIQAAK DGVSKTLNNL
     TDQYNAASER IDTLMTRYKA QFTQLDVLMN SLNSTSSYLT QQFDTSNSNS K
//
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