ID S2J0P1_MUCC1 Unreviewed; 1024 AA.
AC S2J0P1;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Alpha 1,4-glycosyltransferase domain-containing protein {ECO:0000259|Pfam:PF04572};
GN ORFNames=HMPREF1544_09612 {ECO:0000313|EMBL:EPB83631.1};
OS Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS agent) (Calyptromyces circinelloides).
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB83631.1, ECO:0000313|Proteomes:UP000014254};
RN [1] {ECO:0000313|Proteomes:UP000014254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG The Broad Institute Genomics Platform;
RA Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 32 family.
CC {ECO:0000256|ARBA:ARBA00009003}.
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DR EMBL; KE124064; EPB83631.1; -; Genomic_DNA.
DR AlphaFoldDB; S2J0P1; -.
DR STRING; 1220926.S2J0P1; -.
DR VEuPathDB; FungiDB:HMPREF1544_09612; -.
DR eggNOG; KOG1928; Eukaryota.
DR eggNOG; KOG2288; Eukaryota.
DR InParanoid; S2J0P1; -.
DR OMA; FGKMTNH; -.
DR OrthoDB; 1655383at2759; -.
DR Proteomes; UP000014254; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
DR GO; GO:0016758; F:hexosyltransferase activity; IEA:InterPro.
DR GO; GO:0034599; P:cellular response to oxidative stress; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR Gene3D; 3.90.550.20; -; 1.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR007652; A1-4-GlycosylTfrase_dom.
DR InterPro; IPR002659; Glyco_trans_31.
DR InterPro; IPR007577; GlycoTrfase_DXD_sugar-bd_CS.
DR InterPro; IPR021100; N-glycosylation_EOS1.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR11214:SF387; BETA-1,3-GALACTOSYLTRANSFERASE 6; 1.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR Pfam; PF12326; EOS1; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
DR Pfam; PF04572; Gb3_synth; 1.
DR Pfam; PF04488; Gly_transf_sug; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000014254};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..194
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 738..829
FT /note="Alpha 1,4-glycosyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04572"
FT REGION 1001..1024
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1024 AA; 118236 MW; 3376CAA0F63E7F91 CRC64;
MAQKRIISSL NVPRRYEVPV AILRATSFVP ATLNVIHNLK TAWRVPLRDA GGPLTIQTTQ
AEYYVAVLWC ILAGYWSWIL TTSMMKRWLY HYEIKHAIIR LLTLIVVTWC LSGLITSTID
PTDPIRIQMT LCFVLLLFNF LKLTFASSPK YSQKLEDVLP TARFNLKSTA VRILLLPLLV
VMALSAFVLT GQINRFQYAN ILLMNQKQFE LDSTVSPAAT GGLTILVLIV SSWTSQGAEK
RQLLRDSSLH WTGKESDTNI IYRFVVGQPP SSRIQSWMGP KMVAESEKYH DLLVVPAPDL
PSDKSKKVYE ALRWASSSVQ HDYLIKTDDD VFVRWDVVRK ELAALGPRDN HWQGFVYRNM
PVNFFNPSKS MLIDYGMPVL PTFTSGTLYT LSRNMVGLIA QIDYPQRFIE ADDVNLAMWL
FGFDVQPIHD KRIQDSSDVC EESMIAKRIS YDKFKSTVNT LYNNILHKDP QCISLNKLKK
CATCYPCHGK SDDWRSHNLD CNPSRGVSLL KQPDYVKIPG PNVKDQLEPS VIGENDQWII
KDILSAKTSV YTEDEANWHL LYWVCWTSDP STFTDRHWRA LEMVWIHEPN AVIIMMSNSL
PENFFHDYTR RGYNIQVVNF NKENLLKWNW YFGPGTQDWL QDWDKWEKGK FFYWHLTDYI
RCLLLYNYGG TYMDMDALWI RIPPDQNLEF IGSDYSSVHS DREWTLDDKG LYLPQGLMRF
KRGWKLFREM AEGAFSAFNY DPECFNCGGP KAITSYVRQR RGVLEDAGLT ILPRKVLYPF
SYLEIHKLLQ PNALAEQEMK NKIEPYSWNI HLFGKMTNHL PVQPNSVIDY VFKKFDLDLP
HRDTSSHKII SSTQSMTVPM HLVGPRDYIY KAISERMLED DRKKENLLRL QPTPGKFQGI
NVIYVRGGPD RIPKVTIELD TAIGRSSINN GTHEKQIMFE LQNVSMKEVN SALNSIEYSP
PALMLANGGR DRLKVDVTYD HGGQYIEKGQ LQITVVVMEP EEEDDKLEDD REDEALLLNK
KKKD
//
