ID   S2J1K2_MUCC1            Unreviewed;       355 AA.
AC   S2J1K2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN   ORFNames=HMPREF1544_09331 {ECO:0000313|EMBL:EPB83941.1};
OS   Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS   agent) (Calyptromyces circinelloides).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB83941.1, ECO:0000313|Proteomes:UP000014254};
RN   [1] {ECO:0000313|Proteomes:UP000014254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KE124054; EPB83941.1; -; Genomic_DNA.
DR   AlphaFoldDB; S2J1K2; -.
DR   STRING; 1220926.S2J1K2; -.
DR   VEuPathDB; FungiDB:HMPREF1544_09331; -.
DR   eggNOG; KOG1198; Eukaryota.
DR   InParanoid; S2J1K2; -.
DR   OMA; AVGKYKK; -.
DR   OrthoDB; 1788094at2759; -.
DR   Proteomes; UP000014254; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08267; MDR1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014254}.
FT   DOMAIN          14..352
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   355 AA;  38391 MW;  B60796D9206EE77E CRC64;
     MSTTMHALQL VKYGSPEEAF LYNEQAPKPT IKSKTEVLVR IKAAGANPVE AKAASGNMKL
     ALSTMKMPKV LGSDFSGIIE QVGSAVKDFQ VGDEVFGTLH LPIFLEGTFA QYTVVDTAKK
     SIAKKPAHLS FEQAASTGIA AITAYQGIII NGKTSKNPDV PRKILIVGAS GGVGSYGIQF
     AKAINKENTV VGICSGSNAE FIKSLGADRA VDYKDKAAYE SFITEEKGTF DVVLDCVGGE
     DYFNQLDPLL KKGGVYSTAV GPMEHAGSEY IGITQFASMV SKLIYKKLFG RHAYYFIHTL
     PYADFKDKVS KFFESEAVHG TVVDDSNIIP LKEGVRAFEK LNTHRTIGKI VFKID
//