ID   S2JRP6_MUCC1            Unreviewed;      1444 AA.
AC   S2JRP6;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=Phosphorylase kinase alphabeta {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1544_10788 {ECO:0000313|EMBL:EPB82450.1};
OS   Mucor circinelloides f. circinelloides (strain 1006PhL) (Mucormycosis
OS   agent) (Calyptromyces circinelloides).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=1220926 {ECO:0000313|EMBL:EPB82450.1, ECO:0000313|Proteomes:UP000014254};
RN   [1] {ECO:0000313|Proteomes:UP000014254}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1006PhL {ECO:0000313|Proteomes:UP000014254};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., Earl A., Findley K., Lee S.C., Walker B., Young S., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome sequence of Mucor circinelloides f. circinelloides 1006PhL.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Glycan biosynthesis; glycogen metabolism.
CC       {ECO:0000256|ARBA:ARBA00005131}.
CC   -!- SIMILARITY: Belongs to the phosphorylase b kinase regulatory chain
CC       family. {ECO:0000256|ARBA:ARBA00007128}.
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DR   EMBL; KE124113; EPB82450.1; -; Genomic_DNA.
DR   STRING; 1220926.S2JRP6; -.
DR   VEuPathDB; FungiDB:HMPREF1544_10788; -.
DR   eggNOG; KOG3635; Eukaryota.
DR   InParanoid; S2JRP6; -.
DR   OMA; CFLMLDA; -.
DR   OrthoDB; 3640971at2759; -.
DR   UniPathway; UPA00163; -.
DR   Proteomes; UP000014254; Unassembled WGS sequence.
DR   GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR   GO; GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR011613; GH15-like.
DR   InterPro; IPR039477; ILEI/PANDER_dom.
DR   InterPro; IPR045583; KPBA/B_C.
DR   InterPro; IPR008734; PHK_A/B_su.
DR   PANTHER; PTHR10749; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR10749:SF8; PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA; 1.
DR   Pfam; PF00723; Glyco_hydro_15; 1.
DR   Pfam; PF15711; ILEI; 1.
DR   Pfam; PF19292; KPBB_C; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 2.
PE   3: Inferred from homology;
KW   Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022600};
KW   Glycogen metabolism {ECO:0000256|ARBA:ARBA00022600};
KW   Reference proteome {ECO:0000313|Proteomes:UP000014254}.
FT   DOMAIN          13..997
FT                   /note="GH15-like"
FT                   /evidence="ECO:0000259|Pfam:PF00723"
FT   DOMAIN          1131..1220
FT                   /note="ILEI/PANDER"
FT                   /evidence="ECO:0000259|Pfam:PF15711"
FT   DOMAIN          1267..1433
FT                   /note="Phosphorylase b kinase regulatory subunit alpha/beta
FT                   C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19292"
FT   REGION          707..742
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          785..825
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1073..1094
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        789..825
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1444 AA;  161666 MW;  7690E9728F013657 CRC64;
     MKSSYNRKHS LERLDYYYQV INTTVLSKQN AASGLIPASV AITTHGDYTD AWVRDNVYSI
     YCVFGLALAY RRVDDTTGRA FELEHAVIKL MRGLLFSMMR QAPKVEKFKK TQNVLDALHA
     KYKTETGATV VGDKDWGHLQ IDATSFFLVA LADMTTSGLS IIYTQDEVDF IQNLVFYIER
     AYRTPDFGIW ERGDKSNHGE PELNSSSIGM AYSALRAING VNLFGARGSA SSTIYVLPDE
     MTRNKITLQS VLPRESNSKE VDGSVLSVIG FPAFAVEDPA LIEFTRSDAK KKLEGRYGWK
     RFLRDGHQTV VEDHTRLHYN ESELKVFENI ESEWPLFFTY MVLEGLFTDN MEQAEEYRKK
     LEFVTIDSAL WDPENPRPPE DYKSEDCKRP AALCRTASLD LSTAPADLHI PLVPELYYVP
     SESIDAERAN PHSQKRIPND NTPLVWALSL YLLGNLIYEN LLSPSEIDPL GRRFNVKGAK
     ADNVVQVVLL SENEELQKTL STYGLETQSI DQISSSFTVL PPQALVDVYS ALGQNSKLEL
     SGRPNRPIGT LTTSRLYRIE GHIYAFTPQF MDVRTFYLNS DPDYLVSTFE NEISVTNANW
     IFAGRPTITI VLTNAMLGDI NRKEVAPKSC SAELTNALLS ADASKKNLLN FFMNLRSGEC
     NGVRVRLSRL AETVNTSNIE SLDFLINKQD VDWSNILSAN KSYHRNSRSQ RRLGFEEASN
     ISSPGGALTP GGARTPRRRS VFGGKLLGTP LNKIDGDSYF QDIASALERI NGDGVPAFKL
     KDHEITSASD SATPRSTASP DPSQMKANGD ASDKNRNTAN LTVDTDESTG NDVLLSLTLG
     DLSQFDDAVK SLQASVNLYD QIDLLQYLAS CKNLDEFIVD LDSTIRNLLE EVYVKSKRLQ
     YWSVVRQASG LLSKTMPTLT YNLTDLVIHK KQVSIGSGSS EHLISTPLGP DTLNKMIAEQ
     CVDDVREGPV VQEIIISLGN FIRSNPRMFD GILRLRTHFI IIALREEISR LNDFNEEEAI
     EHLMQLSPFE LQSLLGTVMS GPGMCEETTI IVRDKPGGFL VLSQDFDPNR QLSNEVPSLT
     LPPAKNKTES KDIENPDKKD TIIIRAQSGG YNAGNFARAE INGNVLAANT RGLHVWAIDR
     LEKLVLEHAS FDTHISSDES EDLVQFIRNL DSGLIVVMAS KDDFSEHLTK EAVDAIKSLG
     AQKIDDVKYR DSYVLIAEKN GNRTIEAHKA AKDGPTDLIE EEFAMLKKHD ISPSDINDSN
     ISHFCPSSNG RWLRRRKNDG ALNRAPKHFF SRTWKVLDHC AGLVIGSHCL PRDPTVFEKT
     PEEFNFALAV EGFLGTLRDP AERQVAVELL TQIYEMQKAK PEFQFIDQNI DILAIMDGAI
     SDFWNTWVGK NKETFEKSPM FEHGFDYNAH KEMAHGLFYD LPLDHAEEST ATYLRKSISN
     ALHI
//