ID S2NBT0_LACPA Unreviewed; 430 AA.
AC S2NBT0;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zn-dependent peptidase, M16 family {ECO:0000313|EMBL:EPC37400.1};
GN ORFNames=Lpp225_1774 {ECO:0000313|EMBL:EPC37400.1};
OS Lacticaseibacillus paracasei subsp. paracasei Lpp225.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=1256225 {ECO:0000313|EMBL:EPC37400.1, ECO:0000313|Proteomes:UP000014270};
RN [1] {ECO:0000313|EMBL:EPC37400.1, ECO:0000313|Proteomes:UP000014270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lpp225 {ECO:0000313|EMBL:EPC37400.1,
RC ECO:0000313|Proteomes:UP000014270};
RX PubMed=23894338;
RA Smokvina T., Wels M., Polka J., Chervaux C., Brisse S., Boekhorst J.,
RA van Hylckama Vlieg J.E., Siezen R.J.;
RT "Lactobacillus paracasei comparative genomics: towards species pan-genome
RT definition and exploitation of diversity.";
RL PLoS ONE 8:E68731-E68731(2013).
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPC37400.1}.
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DR EMBL; ANMM01000013; EPC37400.1; -; Genomic_DNA.
DR RefSeq; WP_016385451.1; NZ_ANMM01000013.1.
DR AlphaFoldDB; S2NBT0; -.
DR PATRIC; fig|1256225.3.peg.1842; -.
DR Proteomes; UP000014270; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR43690:SF18; INSULIN-DEGRADING ENZYME-RELATED; 1.
DR PANTHER; PTHR43690; NARDILYSIN; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 62..149
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 181..362
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 430 AA; 47372 MW; 7FE5F06DE0319059 CRC64;
MKTQYFSDVD ETVITTTLSN GLRLQVVPRP AYHKSYAIMT TDYGSIDTQF APDGKQMVTY
PAGIAHFLEH KLFEKEDHDA FDLFGETGAS ANAFTSATKT SFLFSTTTQL TKNLQILLDF
VQTPFFSKAS VAKEQGIIGS EIQMYQDDPG WRGYAGLLEN LFPNHPAHVD VAGTVASIAQ
ITPEMLYTIH RVFYQPSNMT LIVVGNIDAD AIMAFVAANQ AAKQFPAPQA IVRGVHADLQ
TDDIVPYRQL EMPISRPKTL VGIKGQVAIP TTAEGWRYQL TIRLLLEVLF GDSSQLYQDW
YDRGLIDDSF DFDFTNQRSF SYGLVGGDTD DPHALSDAIK HVLLNAATQP DLTRDRVALI
KRASLGKYYA GLNGLNGVAN QLSALSFGQA SLFDFPEILS SITLADLQAV IDQVFQAKAL
TVLDMIPEAD
//
