ID   S2NGF7_LACPA            Unreviewed;       762 AA.
AC   S2NGF7;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:EPC38955.1};
GN   ORFNames=Lpp225_0426 {ECO:0000313|EMBL:EPC38955.1};
OS   Lacticaseibacillus paracasei subsp. paracasei Lpp225.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lacticaseibacillus.
OX   NCBI_TaxID=1256225 {ECO:0000313|EMBL:EPC38955.1, ECO:0000313|Proteomes:UP000014270};
RN   [1] {ECO:0000313|EMBL:EPC38955.1, ECO:0000313|Proteomes:UP000014270}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Lpp225 {ECO:0000313|EMBL:EPC38955.1,
RC   ECO:0000313|Proteomes:UP000014270};
RX   PubMed=23894338;
RA   Smokvina T., Wels M., Polka J., Chervaux C., Brisse S., Boekhorst J.,
RA   van Hylckama Vlieg J.E., Siezen R.J.;
RT   "Lactobacillus paracasei comparative genomics: towards species pan-genome
RT   definition and exploitation of diversity.";
RL   PLoS ONE 8:E68731-E68731(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPC38955.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ANMM01000002; EPC38955.1; -; Genomic_DNA.
DR   RefSeq; WP_003567804.1; NZ_ANMM01000002.1.
DR   AlphaFoldDB; S2NGF7; -.
DR   PATRIC; fig|1256225.3.peg.432; -.
DR   Proteomes; UP000014270; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR048228; HelD_bacillota.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR027785; UvrD-like_helicase_C.
DR   NCBIfam; NF041464; HelD_BACSU; 1.
DR   PANTHER; PTHR11070:SF2; ATP-DEPENDENT DNA HELICASE SRS2; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13538; UvrD_C_2; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}.
FT   DOMAIN          207..593
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         228..235
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   762 AA;  85681 MW;  CFEDBC1EFF815167 CRC64;
     MENATKAEEQ ARVTAVIEKL KARLAAIHDQ IEAAHKETSR IERSYGENTK VNVTEVDDQM
     ETNAAVQQQK VMVARAVENE TILKHEGNRL TLLADNPYFG RIDIDEDGDP DTLYIGTATF
     IDQDGEFLVY DWRAPVSSIY YNGTLGDVSY DTPAGEQHAT LKNKRQFQIE HGHIKTMFDT
     NETVGDEILQ SVLGDQSDEY MKNIVATIQR EQNDIIRDTT SDLLVVQGVA GSGKTSAVLQ
     RIAYLLYHSR SDLDADQMVL FSPNRLFANY ISQVLPSLGE KNMRQATLFE FLANRFTGLH
     VETLFERYEH DAAGLPPAAE HIRRFKEAPR YLEAIYDYAK QPKRTPHFID VEFNGETFFS
     AATIAKIYQA QPALMQPVDK FTATKNALIK RLNTRIHMEA KRDWAQLRVS DLSQTELETL
     TADHEFETGE DEQRFVSEAI VSKAFSPIYD ALYNDHFYDV FQDYQQFMAQ VKPPVAPAIW
     HTMVNAFSDG IEAHQLRLED AAPLLYLRDL STGSGQNSLI QYVFVDEMQD FSMAQLLYLK
     HAFPKAKLTL LGDAKQDVFT SNYQPSDFIH EIEDVFSGYK IRLITLNKSY RSTQPITNFA
     KALLPEHDHI QAFNRAGDKP EVLTVARTEA PDALSKLVTQ LLATDTTVAI LTKDAQTADQ
     LYATLKLDAP VTLLSANDHS LKNGCVILPV YLAKGLEFDA VIGWDISATT YQNEADRDIL
     YTLCSRALHH LTLVALDAPS PLITALPADL YTHAGDASEA RV
//