ID S2XP49_9BACL Unreviewed; 572 AA.
AC S2XP49;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=HMPREF1210_00083 {ECO:0000313|EMBL:EPD54098.1};
OS Paenisporosarcina sp. HGH0030.
OC Bacteria; Bacillota; Bacilli; Bacillales; Planococcaceae;
OC Paenisporosarcina.
OX NCBI_TaxID=1078085 {ECO:0000313|EMBL:EPD54098.1, ECO:0000313|Proteomes:UP000014412};
RN [1] {ECO:0000313|EMBL:EPD54098.1, ECO:0000313|Proteomes:UP000014412}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HGH0030 {ECO:0000313|EMBL:EPD54098.1,
RC ECO:0000313|Proteomes:UP000014412};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Paenisporosarcina sp. HGH0030.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPD54098.1}.
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DR EMBL; AGEQ01000003; EPD54098.1; -; Genomic_DNA.
DR RefSeq; WP_016426598.1; NZ_KE150421.1.
DR AlphaFoldDB; S2XP49; -.
DR STRING; 1078085.HMPREF1210_00083; -.
DR PATRIC; fig|1078085.3.peg.63; -.
DR eggNOG; COG0365; Bacteria.
DR HOGENOM; CLU_000022_59_10_9; -.
DR Proteomes; UP000014412; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000014412}.
FT DOMAIN 54..418
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 471..549
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 572 AA; 64818 MW; D5703D08A8B39A5D CRC64;
MKLEVLPVVQ GDYLLQNYDE TAANFDWKEA EKAFSWHVTG RMNVAHEAID RHANSDRKNK
IALYYKDAIR KESYTFNEMK KWTNKAANAL KAHTNLEKGD RLFIFMPRSP ELYFALIGAL
KMGVIVGPLF EAFMEGAVYD RLADSEAKAI VTTPELLNRI PVDKLPHLET ILLVGENVEE
DNKTVDFMKH LKAASQYFQV EWLDKEDGLV LHYTSGSTGK PKGVLHVQEA MVQHYQTAKW
VLDLKEQDIY WCTADPGWVT GTSYGIFGPW LTGTTMVVLG GRFSPDAWYQ AIEDFGVTIW
YSAPTAFRML MGAGDALVKE YDLSSLRHVL SVGEPLNPEV IRWGAEVFRH RIHDTWWMTE
TGAQMICNYA CLPIRPGSMG KPIPGVKAAI VDDRGVELPP YQMGNLALKK GWPSMMRQIW
NNPEKYQSYF LNDEWYVSGD SAYMDEDGYF WFQGRIDDVI MTSGERVGPF EVESKLLEHP
SIVEAGVIGK PDPVRGEIIK AFVALKEGVE PSDELIADIQ QFVKKGLAAH AAPREIEFKD
KLPKTRSGKI MRRVLKAWEL DLPTGDLSTM ED
//
