ID   S2XZ42_9STAP            Unreviewed;       413 AA.
AC   S2XZ42;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   27-MAR-2024, entry version 43.
DE   RecName: Full=Sialidase domain-containing protein {ECO:0000259|Pfam:PF13088};
GN   ORFNames=HMPREF1208_01291 {ECO:0000313|EMBL:EPD50412.1};
OS   Staphylococcus sp. HGB0015.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=1078083 {ECO:0000313|EMBL:EPD50412.1, ECO:0000313|Proteomes:UP000014407};
RN   [1] {ECO:0000313|EMBL:EPD50412.1, ECO:0000313|Proteomes:UP000014407}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HGB0015 {ECO:0000313|EMBL:EPD50412.1,
RC   ECO:0000313|Proteomes:UP000014407};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Schmidt T.M., Dai D., Dover J.,
RA   Kim K., Walker B., Young S., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Allen A.W., Alvarado L., Arachchi H.M., Berlin A.M.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sisk P.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Staphylococcus sp. HGB0015.";
RL   Submitted (APR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPD50412.1}.
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DR   EMBL; AGEO01000013; EPD50412.1; -; Genomic_DNA.
DR   AlphaFoldDB; S2XZ42; -.
DR   PATRIC; fig|1078083.3.peg.1267; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024974_0_0_9; -.
DR   Proteomes; UP000014407; Unassembled WGS sequence.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   InterPro; IPR023364; Trans_sialidase_dom3.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000014407};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..413
FT                   /note="Sialidase domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004503560"
FT   DOMAIN          265..386
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   413 AA;  47029 MW;  C7FC751047524F12 CRC64;
     MKYLFKFSLL LLISLLLSMF LITNINALAK DKVTMDKDIF TAGDETQANY FRIPVLYTLN
     NGNIIASADA RYGGTHDAKS KINIATSISE DGETWSSPKL ALHFQDYENQ LIDWPRDNVG
     KNKQIQGSAS FIDSAIVQDK KTNTIFLMAD MMPAGVGNNN ALKNDSGFKK INENYYLKLK
     FENDNNYDYS IREDGLIFND KQQKPTEYKV DENYNILKNG EYQYVTQYSV RFNGNELKEY
     HNGKKVKMNI FYKDSIFKVT PTNYLAYTTS DDGKNWNHPM ILPPFLGLNH NATYLSPGQG
     LATSNGRLIF SSYTSQGLIF IYSDDHGYTW KSTKAELPFK NATVEAQMIE LKPGVIKAFL
     RTTTGKIGYM TSYDHGNTWD KVRYLNQIKQ TRYGTQLSVI KASKKVEGKD VII
//