ID   S3BCZ2_9FLAO            Unreviewed;       700 AA.
AC   S3BCZ2;
DT   18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT   18-SEP-2013, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Alpha-glucosidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF1528_02063 {ECO:0000313|EMBL:EPD98301.1};
OS   Capnocytophaga sp. oral taxon 336 str. F0502.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Capnocytophaga.
OX   NCBI_TaxID=1203603 {ECO:0000313|EMBL:EPD98301.1, ECO:0000313|Proteomes:UP000014404};
RN   [1] {ECO:0000313|EMBL:EPD98301.1, ECO:0000313|Proteomes:UP000014404}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0502 {ECO:0000313|EMBL:EPD98301.1,
RC   ECO:0000313|Proteomes:UP000014404};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Kirega A., Tanner A.C.,
RA   Dewhirst F.D., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Capnocytophaga sp. oral taxon 336 F0502.";
RL   Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC         Evidence={ECO:0000256|ARBA:ARBA00001913};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EPD98301.1}.
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DR   EMBL; ATCI01000023; EPD98301.1; -; Genomic_DNA.
DR   RefSeq; WP_016479672.1; NZ_KE150492.1.
DR   AlphaFoldDB; S3BCZ2; -.
DR   PATRIC; fig|1203603.3.peg.2021; -.
DR   HOGENOM; CLU_011166_2_0_10; -.
DR   Proteomes; UP000014404; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR029483; GH97_C.
DR   InterPro; IPR019563; GH97_catalytic.
DR   InterPro; IPR029486; GH97_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35803:SF1; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB; 1.
DR   PANTHER; PTHR35803; GLUCAN 1,4-ALPHA-GLUCOSIDASE SUSB-RELATED; 1.
DR   Pfam; PF14509; GH97_C; 1.
DR   Pfam; PF14508; GH97_N; 1.
DR   Pfam; PF10566; Glyco_hydro_97; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..700
FT                   /note="Alpha-glucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004506148"
FT   DOMAIN          24..290
FT                   /note="Glycosyl-hydrolase 97 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14508"
FT   DOMAIN          295..596
FT                   /note="Glycosyl-hydrolase 97 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF10566"
FT   DOMAIN          599..700
FT                   /note="Glycosyl-hydrolase 97 C-terminal oligomerisation"
FT                   /evidence="ECO:0000259|Pfam:PF14509"
SQ   SEQUENCE   700 AA;  79456 MW;  2D8ED02756218618 CRC64;
     MKKFIITIVC MLCAAPLLFA QTLLSPNENL KLSFRLTEKG TPTYALTFKG KTVISESALG
     FVINQKEDFN SNFEITDVQF AEANSVWQPV LGENKEIRDH HKEMLVHLSQ KNSGRQLLLR
     FRLFNDGLGF RYEFPLQDNF RHFRIQEELT VFQLSGNHKA FWIPADYDTN EFPITTSAIS
     EIPKLIDKVR EEPLAAKAPT PNVAVQTPLM LKSSDGLYIN LHEAALVNYP AMMLNVNATK
     HQLSAHLVPD KNGVKGYIQT GSVTPWRTIV VSDDARDILA SNLILNLNDP CKITDTSWIH
     PTKYIGVWWE YFIGGGSTWA YSDDRDITIG VTDYTKLKPN GHHGANTEHV KKYINFASQH
     GFDAVLVEGW NEGWEDNYAY NKERIYSFTK AYPDFDVQAL HQYAAAKGVK LIMHHETTSS
     VVDYERHLHE AFRFMNDNGY DAVKTGYVGP IIPRSEYHDG QWMVNHYNYV AETAAKYRIM
     VNSHEAVRPT GMSRTYPNWV AQESARGTEF ESFNGNHPEH TTILPFTRLM GGAMDYTPGI
     FEGDLSRYGN NKAKRSTTLV KQLALYVTMY SPLQMAADLP ENYEKHLDAF QFIKDVAADW
     DNTYILEAEP GDYITIARKA KGKNEWFVGA ITDENAREAL VDFSFLPKGK TYTATLYTDG
     KNADWRTNPN SYSIKTMKVT QKTKLKQRLA PSGGLAISIK
//