ID S3C3J6_OPHP1 Unreviewed; 1125 AA.
AC S3C3J6;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Elongation factor 3 {ECO:0000313|EMBL:EPE08094.1};
GN ORFNames=F503_00877 {ECO:0000313|EMBL:EPE08094.1};
OS Ophiostoma piceae (strain UAMH 11346) (Sap stain fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Ophiostoma.
OX NCBI_TaxID=1262450 {ECO:0000313|EMBL:EPE08094.1, ECO:0000313|Proteomes:UP000016923};
RN [1] {ECO:0000313|EMBL:EPE08094.1, ECO:0000313|Proteomes:UP000016923}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 11346 {ECO:0000313|EMBL:EPE08094.1,
RC ECO:0000313|Proteomes:UP000016923};
RX PubMed=23725015; DOI=10.1186/1471-2164-14-373;
RA Haridas S., Wang Y., Lim L., Massoumi Alamouti S., Jackman S., Docking R.,
RA Robertson G., Birol I., Bohlmann J., Breuil C.;
RT "The genome and transcriptome of the pine saprophyte Ophiostoma piceae, and
RT a comparison with the bark beetle-associated pine pathogen Grosmannia
RT clavigera.";
RL BMC Genomics 14:373-373(2013).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC EF3 subfamily. {ECO:0000256|ARBA:ARBA00011054}.
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DR EMBL; KE148149; EPE08094.1; -; Genomic_DNA.
DR AlphaFoldDB; S3C3J6; -.
DR STRING; 1262450.S3C3J6; -.
DR VEuPathDB; FungiDB:F503_00877; -.
DR eggNOG; KOG0062; Eukaryota.
DR eggNOG; KOG1242; Eukaryota.
DR HOGENOM; CLU_002848_0_1_1; -.
DR OMA; EDHRKFG; -.
DR OrthoDB; 49929at2759; -.
DR Proteomes; UP000016923; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03221; ABCF_EF-3; 1.
DR CDD; cd18626; CD_eEF3; 1.
DR Gene3D; 2.40.50.990; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR015688; eEF3_ABC2_chromodomain-like.
DR InterPro; IPR047038; eEF3_chromodomain-like_sf.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19211:SF14; ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3; 1.
DR PANTHER; PTHR19211; ATP-BINDING TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 3.
DR Pfam; PF00385; Chromo; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Elongation factor {ECO:0000313|EMBL:EPE08094.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EPE08094.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000016923};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT REPEAT 209..247
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 475..692
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 720..1037
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1022..1125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1055..1071
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1091..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1125 AA; 122749 MW; 5216863ABCB9ED6F CRC64;
MDGTAIAHRP AKDGKAEVAA VLSAVFSAST SNASVEAAYQ LCDLLLNNPA AGFRGLAEYG
VLAEIKKAAA DKKSGLRRES AQNLLGALFE RFPPKQAASE VAFLLQDGGM VAVALDALAD
KGTVVRNAAQ YGLDALLGHL RAESLVVGLL PALVTYLNKR TGKWQGTVGA LKLLQRMADK
AKMEIGSTKE EAIEKEVLRD LMGSKLASLI PIVEAMMSDL KTEVEKQAVI TMTSITSLLS
NDDVAPRVPL LIDTMQHPSV QSLQKAIHAL AHTTFVAIVT SPVLALLTPF LERSLNTPTT
AQEVLRQTVV ITENLTKLVH DPIEARTFLP KLQPGVKAVR DRAALPEVRD MAARALSVMD
IAMATDKEGK NVAVERVSAD DVAVQLYSEV QKAGGLLPAD ADNFKTISPY ISSMVAEDAN
ARYINRIHTS VAPYLGPLLK NSAAAETIAA AVQQYYLEED QRKFGVPEKE DDGEVEIVNA
DFSLGYGGML LLSHTNMRLL KGHRYGLVGR NGAGKSTLMR SIAGGKLEGF PPQDVLRTCY
VEHNQGEDAE ISILDFVAKD PTIAQEGRER ISAVLLEFGF TDGPDGRQAQ KVGSLSGGWK
MKLALARAML QKADVLLLDE PTNHLDVANI AWLQTYLKTN TEITSLIVSH DSGFLDEVTT
DIYHYEPGKK LAHYKGNLAT FVSNHPEAKS YYTLSDSMVQ FKFPPPGILS GIKSQTRAIV
RMSNVTFAYP GAAAPSLSDA SCQLTLSSRV AVIGPNGAGK STLIKLLTGE VIPTIGKVEK
HPNLRIGYIK QHALEHVEMH LEKTPNQYLQ WRYQFGDDRE VHMKQTRQMS EADRAQMDKI
VELGEGMGQR QIEALVGRQK YKKTFQYEVK WKLMLPKENT MVTRETLLAL GFDKLIQEFD
DHESSREGLS FRELQPAIIS KHFEDLGLDP EIANHNEIGG LSGGQKVKVV IAGAMWNNPH
LLVLDEPTNF LDRDSLGGLA VAIRDFKGGV VMISHNEEFV GALSNEQWHV VAGRMTHRGH
AAVSNDRFED SSRPGSGINT PGVSTPGIMS PGGATPAMSS MQSSAVNSGV EDNATGDLKF
KAKKKRKKTK KDLKEQENRR RQREIVWLNS PKGTPKPLDT DDEEE
//
