ID S3C6A9_9FLAO Unreviewed; 773 AA.
AC S3C6A9;
DT 18-SEP-2013, integrated into UniProtKB/TrEMBL.
DT 18-SEP-2013, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=HMPREF1528_00573 {ECO:0000313|EMBL:EPE01738.1};
OS Capnocytophaga sp. oral taxon 336 str. F0502.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Capnocytophaga.
OX NCBI_TaxID=1203603 {ECO:0000313|EMBL:EPE01738.1, ECO:0000313|Proteomes:UP000014404};
RN [1] {ECO:0000313|EMBL:EPE01738.1, ECO:0000313|Proteomes:UP000014404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0502 {ECO:0000313|EMBL:EPE01738.1,
RC ECO:0000313|Proteomes:UP000014404};
RG The Broad Institute Genomics Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Kirega A., Tanner A.C.,
RA Dewhirst F.D., Izard J., Walker B., Young S., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Capnocytophaga sp. oral taxon 336 F0502.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EPE01738.1}.
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DR EMBL; ATCI01000001; EPE01738.1; -; Genomic_DNA.
DR RefSeq; WP_016478550.1; NZ_KE150488.1.
DR AlphaFoldDB; S3C6A9; -.
DR PATRIC; fig|1203603.3.peg.568; -.
DR HOGENOM; CLU_007082_5_0_10; -.
DR Proteomes; UP000014404; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 31..159
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 162..516
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 642..753
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|Pfam:PF00754"
FT ACT_SITE 349
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 773 AA; 87556 MW; B22CDA47A63CDB31 CRC64;
MKTIKKFLCI SVLWVVACQS QKEAVFTMKD LAVIPQPKSV VLGKGSFRFT KETVFVIDPA
LMPARRSFLE QFEKASGFRF SVQKVALLTN YVVIDTDTSL PKEGYTLTVN PKEIIIKAGG
YNGALYALET LRQLLPKEFE STTPVKTDWA VPAVTITDAP QYAWRGLMLD VSRHFFPKEY
ILKTLDRMAM LKLNTFHFHL VDNEGWRIEI KKYPKLTEIG AWRVDQEDKL WNERTPNSAN
AFANPATAPK KYGGFYTQED IKEIVAYASA RGITVIPEIE MPAHAMSAIA AYPKLSCHKR
PIGVPSGAVW PITDIYCAGQ EETFTFLEDV LTEVMELFPS KYIHVGGDEA THTEWKKCLK
CQARMKDHHL KDVHQLQSYF IKRINDFLVS KGRTLVGWDE IMDRGLANNA VVMNWRGIEV
GKKALEQGNP VVLTSDCYID NYQGLPDYEP QANGGYLPLK TLYHYSLEKE NLSPALQKNI
LGTQANLWAE HVGSTEHSEY MLFPRLLALA EISWTTDNLK NWDNFINRTQ AFMKRLDVMK
VNYARSMYQV VPTVENQKGN IFLKLDCEVP NADIRYALGD TPMEKATKYR QPIALNRSTT
FKATVFSGKA TNTITTGEVT FHKAIDKKVS YSPLYHKSYQ GQGEATLTNV IRGTKNFHDG
QWLGWLGDDV TLTLNLEQAT EVREVRIGAM DAQASGIYFP VEFIVSLSND GKNYREVATH
NEPCVVRGKA TLKDFVLKFS PTEARYIKLT LKNVKTPPKG GDAWLFIDEI LVF
//
